acth

What is ACTH?


Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.

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Also known as Corticotropin, Adrenocorticotropin, Adrenocorticotropic Hormone, Corticotrophin, Adrenocorticotrophic Hormone, ACTH (1-39), serum adrenocorticotropic hormone, 1-39 ACTH, Corticotropin (1-39), Corticotrophin (1-39)
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ACTH information from trusted sources:

Corticotropin

To help diagnose adrenal and pituitary diseases such as Cushings syndrome, Cushings disease, Addisons disease, adrenal tumors, and pituitary tumors

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ACTH

An ACTH test measures ACTH, a hormone released from the anterior pituitary gland in the brain.

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Cosyntropin

Cosyntropin Injection is a 1 mL sterile solution in vials containing 0.25 mg of cosyntropin, 0.82 mg sodium acetate trihydrate, 6.4 mg sodium chloride, 10 mg mannitol, 1 mg glacial acetic acid, and water for injection, USP. Administration is by intravenous injection. Cosyntropin is α 1-24 corticotropin, a synthetic subunit of ACTH. It is an open chain polypeptide containing, from the N terminus, the first 24 of the 39 amino acids of natural ACTH. The sequence of amino acids in the 1-24 compound is as follows:... ... Cosyntropin injection is intended for use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency. Because of its rapid effect on the adrenal cortex it may be utilized to perform a 30-minute test of adrenal function (plasma cortisol response) as an office or outpatient procedure, using only 2 venipunctures (see DOSAGE AND ADMINISTRATION section).

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Cortrosyn

CORTROSYN (cosyntropin) for Injection is a sterile lyophilized powder in vials containing 0.25 mg of CORTROSYN and 10 mg of mannitol to be reconstituted with 1 mL of 0.9% Sodium Chloride Injection, USP. Administration is by intravenous or intramuscular injection. Cosyntropin is α 1 – 24 corticotropin, a synthetic subunit of ACTH. It is an open chain polypeptide containing, from the N terminus, the first 24 of the 39 amino acids of natural ACTH.

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Cortrosyn

Somatrem and somatropin are man-made versions of human growth hormone. Growth hormone is naturally produced by the pituitary gland and is necessary to stimulate growth in children. Man-made growth hormone may be used in children who have certain conditions that cause failure to grow normally. These conditions include growth hormone deficiency (inability to produce enough growth hormone), kidney disease, Prader-Willi Syndrome (PWS), and Turner's syndrome. Growth hormone is also used in adults to treat growth failure and to treat weight loss caused by acquired immunodeficiency syndrome (AIDS).

Read more on www.mayoclinic.com

Adrenocorticotropic hormone - Wikipedia, the free encyclopedia

Adrenocorticotropic hormone (ACTH), also known as 'corticotropin', is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. ...

Read more on en.wikipedia.org

Medicines for Epilepsy: ACTH

ACTH has been used since the late 1950's to treat infantile spasms although this use has not been submitted to the U.S. Food and Drug Administration for ...

ACTH Deficiency - Disease Information from NORD, National ...

Dec 31, 2010 ... ACTH deficiency arises as a result of decreased or absent production of ... A decline in the concentration of ACTH in the blood leads to a ...

Read more on www.rarediseases.org

Contents

Considerations
Special handling of the blood sample is required.

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How the Test Will Feel
When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.

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How to Prepare for the Test
The health care provider may advise you to stop taking steroid drugs. You may need to be at the laboratory or office where the blood is being drawn by or before 8 a.m.

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Indications
This test can help find the causes of hormone problems.

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Normal Results
Normal values: 9 - 52 pg/mL

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Risks
Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

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What Abnormal Results Mean
Higher than normal levels of ACTH may be due to: Addison's disease ; Adrenoleukodystrophy (very rare); Cushing's disease ; Ectopic tumor producing ACTH ; Nelson's syndrome (very rare); Cushing syndrome related to adrenal tumor ; Exogenous Cushing syndrome ; Pituitary insufficiency; Hypopituitarism ; Multiple endocrine neoplasia (MEN) I

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