cholinesteraseinhibitors

What is cholinesterase inhibitors?


Serum cholinesterase is a test that looks at blood levels of certain enzymes (acetylcholinesterase and pseudocholinesterase) that help the nervous system work properly. Acetylcholinesterase (also known as RBC cholinesterase) and pseudocholinesterase (also known as butyrylcholinesterase or plasma cholinesterase) help break down a chemical that nerves need to send signals. Acetylcholinesterase is found in nerve tissue and red blood cells. Pseudocholinesterase is found primarily in the liver.

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Pralidoxime Injection

PRALIDOXIME CHLORIDE INJECTION (AUTO-INJECTOR) - Pralidoxime Chloride Injection (auto-injector) provides pralidoxime chloride in a sterile solution for intramuscular injection. Each prefilled auto-injector provides a dose of the antidote, pralidoxime chloride in a self-contained unit, specially designed for automatic self- or buddy- administration by military personnel. Pralidoxime in the auto-injector may also be administered by qualified civilian emergency responders who have had adequate training in the on-site recognition and treatment of nerve agent intoxication in the event of an accidental release of nerve agent. The recommended procedure (see DOSAGE AND ADMINISTRATION - ) is to inject the contents of the auto-injector into the muscles of an outer thigh. After an auto-injector has been activated, the empty container should be disposed of properly (see DOSAGE AND ADMINISTRATION - ), it cannot be refilled nor can the protruding needle be retracted. When activated, each auto-injector dispenses 600 mg of pralidoxime chloride in 2 mL of a sterile solution containing 20 mg/mL benzyl alcohol, 11.26 mg/mL glycine in Water for Injection, USP. The pH is adjusted with hydrochloric acid. The pH range is 2.0-3.0. The product is pyrogen free. Pralidoxime chloride is a cholinesterase reactivator. Chemical Name: - 2-formyl-1 methylpyridinium chloride oxime (pyridine-2-aldoxime methochloride). Also referred to as 2-PAM Chloride.

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Cholinesterase Inhibitors, Including Insecticides and Chemical ...

Oct 16, 2007 ... This CSEM focuses on cholinesterase inhibitors, including pesticides and chemical warfare nerve agents. The goal of Case Studies in ...

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Cholinesterase inhibitors for Alzheimer's disease.

by J Birks - 2006 - Cited by 436 - Related articles

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Treatments for Alzheimer's Disease topic sheet

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Cholinesterase Inhibitor - Toxipedia

Cholinesterase inhibitors, most notably Organophosphates and Carbamates, bind to the enzyme cholinesterase and do not allow it to break down stimulating ...

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Carbonic Anhydrase Inhibitor

Carbonic anhydrase inhibitors are used to treat glaucoma. Acetazolamide is also used as an anticonvulsant to control certain seizures in the treatment of epilepsy. It is also sometimes used to prevent or lessen some effects in mountain climbers who climb to high altitudes, and to treat other conditions as determined by your doctor.

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Selective serotonin reuptake inhibitors

Selective serotonin reuptake inhibitors (SSRIs) may be taken for:

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Donepezil

Donepezil is the first piperidine-type reversible cholinesterase inhibitor.

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Course Info. - Online Registration and Accreditation (TCEOnline) - CDC

ATSDR Case Studies in Environmental Medicine: Cholinesterase Inhibitors (Web-Based) Course Number: WB1098. ATSDR Case Studies in Environmental Medicine ...

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Aricept: Cholinesterase Inhibitor - HealthyPlace

Apr 12, 2009 ... Anesthesia: ARICEPT®, as a cholinesterase inhibitor, is likely to exaggerate succinylcholine-type muscle relaxation during anesthesia. ...

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Contents

Atropen Auto-Injector
Each prefilled auto-injector provides a dose of the antidote atropine in a self-contained unit, specially designed for self or caregiver administration. Four strengths of AtroPen are available, they are AtroPen 0.25 mg, AtroPen 0.5 mg, AtroPen 1 mg, and AtroPen 2 mg. The AtroPen Auto-Injector is indicated for the treatment of poisoning by susceptible organophosphorous nerve agents having cholinesterase activity as well as organophosphorous or carbamate insecticides. The AtroPenAuto-Injector should be used by persons who have had adequate training in the recognition and treatment of nerve agent or insecticide intoxication. Pralidoxime chloride may serve as an important adjunct to atropine therapy.

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Pralidoxime
PROTOPAM Chloride (pralidoxime chloride) for Injection Rx only - Pralidoxime chloride is a cholinesterase reactivator.

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Malathion Topical
OVIDE Lotion contains 0.005 g of malathion per mL in a vehicle of isopropyl alcohol (78%), terpineol, dipentene, and pine needle oil. Malathion is an organophosphate agent which acts as a pediculicide by inhibiting cholinesterase activity.

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Pralidoxime Injection
Landauer, W.: Cholinomimetic tetrogens. V. The effect of oximes and related cholinesterase reactivators, Teratology 15:33 (Feb.) 1977. Moller, K. O., Jenson-Holm, J., and Lausen, H. H.: Ugeskr. Laeg. 123:501, 1961. Namba, T., Nolte, C.T., Jackrel, Jr., and Grob, D.: Poisoning due to organophosphate insecticides. Acute and chronic manifestations, Amer. J. Med. 50:475 (Apr.) 1971. Arena, J. M.: Poisoning. Toxicology. Symptoms. Treatments, ed. 4, Springfield, Ill., Charles C.Thomas, 1979, p. 133....

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ATNAA
Landauer, W: Cholinomimetic teratogens. V. The effect of oximes and related cholinesterase reactivators. Teratology 15: 33 (Feb) 1977. Moller, K.O., Jensen-Holm, J. and Lausen, H.H.: Ugeskr Laeg. 123: 501,1961. Namba, T, Nolte, C.T., Jackrel, J. and Grob, D: Poisoning due to organophosphate insecticides. Acute and chronic manifestations. Amer. J. Med. 50: 475 (Apr), 1971. Arena, J.M.: Poisoning, Toxicology Symptoms, Treatments, ed. 4, Springfield, IL, Charles C.Thomas, 1979, p. 133. Brachfeld,...

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Quelicin
Drugs which may enhance the neuromuscular blocking action of succinylcholine include: promazine, oxytocin, aprotinin, certain non-penicillin antibiotics, quinidine, β-adrenergic blockers, procainamide, lidocaine, trimethaphan, lithium carbonate, magnesium salts, quinine, chloroquine, diethylether, isoflurane, desflurane, metoclopramide and terbutaline. The neuromuscular blocking effect of succinylcholine may be enhanced by drugs that reduce plasma cholinesterase activity (e.g., chronically...

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Selective serotonin reuptake inhibitors
Clinical depression is not just grief or sadness. It is an illness that can challenge the person's ability to perform even routine daily activities. At its worst, depression may lead the person to contemplate or commit suicide. Depression represents a burden for the person and his or her family. Sometimes that burden can seem overwhelming. Several different types of mood disorders exist.

C1 esterase inhibitor
C1 esterase inhibitor (C1-INH) is a protein found in the fluid part of your blood that controls C1, the first component of the complement system. The complement system is a group of proteins that move freely through your bloodstream. The proteins work with your immune system and play a role in the development of inflammation. There are nine major complement proteins. They are labeled C1 through C9. This article discusses the test that is done to measures the amount of C1-INH in your blood. See also: Complement Complement component 3 (C3) Complement component 4 (C4) CH50 CH100

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Xa inhibition
To monitor low molecular weight heparin (LWMH) therapy and sometimes to monitor unfractionated heparin (UFH) therapy

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Acetylcholinesterase inhibitor - Wikipedia, the free encyclopedia
An acetylcholinesterase inhibitor (often abbreviated AChEI) or anti-cholinesterase is a chemical that inhibits the cholinesterase enzyme from breaking down ...

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Alzheimer's Association - Medications for Memory
Dec 20, 2010 ... Cholinesterase inhibitors are prescribed to treat symptoms related to memory, ... Three cholinesterase inhibitors are commonly prescribed: ...

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