colesevelam information from trusted sources:
WelChol contains colesevelam hydrochloride (hereafter referred to as colesevelam), a non-absorbed, polymeric, lipid-lowering agent intended for oral administration. Colesevelam is a high capacity bile acid binding molecule. Colesevelam is poly (allylamine hydrochloride) cross-linked with epichlorohydrin and alkylated with 1-bromodecane and (6-bromohexyl)-trimethylammonium bromide. Colesevelam is hydrophilic, and insoluble in water.
Colesevelam is used along with diet, weight loss, and exerciseto reduce the amount of cholesterol and certain fatty substances in the blood. Colesevelam may be used alone or in combination with other cholesterol-lowering medications known as statins (atorvastatin [Lipitor], cerivastatin [Baycol], lovastatin [Mevacor], pravastatin [Pravachol], or simvastatin [Zocor]). Colesevelam is also used to control blood sugar levels in patients with type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Colesevelam is in a class of medications called bile acid sequestrants. It works by binding bile acids in your intestines to form a product that is removed from the body.
Colesevelam is used to lower high cholesterol levels in the blood. This may help prevent medical problems caused by cholesterol clogging the blood vessels. This medicine is also used to treat high blood sugar levels for patients with type 2 diabetes .
WelChol is used to lower blood cholesterol levels when diet and exercise prove insufficient. It works by binding with cholesterol-based bile acids to take them out of circulation. This prompts the liver to produce a replacement supply of bile acids, drawing the extra cholesterol it needs out of the bloodstream.
Colesevelam - Wikipedia, the free encyclopedia
Colesevelam is a bile acid sequestrant administered orally. It is developed by Genzyme and marketed in the US by Daiichi Sankyo under the brand name WelChol ...
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by KL Steinmetz - 2002 - Cited by 39 - Related articles