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What is colesevelam?
Colesevelam is used to lower high cholesterol levels in the blood. This may help prevent medical problems caused by cholesterol clogging the blood vessels. This medicine is also used to treat high blood sugar levels for patients with type 2 diabetes .
Read more on www.mayoclinic.com
Also known as Welchol, colesevelam hydrochloride, CholestaGel, GT31-104, GT 31104, GT-31104
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Drugs and Substances
colesevelam information from trusted sources:
Welchol
WelChol contains colesevelam hydrochloride (hereafter referred to as colesevelam), a non-absorbed, polymeric, lipid-lowering agent intended for oral administration. Colesevelam is a high capacity bile acid binding molecule. Colesevelam is poly (allylamine hydrochloride) cross-linked with epichlorohydrin and alkylated with 1-bromodecane and (6-bromohexyl)-trimethylammonium bromide. Colesevelam is hydrophilic, and insoluble in water. Read more on
www.druglib.com
Colesevelam
Colesevelam is used along with diet, weight loss, and exerciseto reduce the amount of cholesterol and certain fatty substances in the blood. Colesevelam may be used alone or in combination with other cholesterol-lowering medications known as statins (atorvastatin [Lipitor], cerivastatin [Baycol], lovastatin [Mevacor], pravastatin [Pravachol], or simvastatin [Zocor]). Colesevelam is also used to control blood sugar levels in patients with type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Colesevelam is in a class of medications called bile acid sequestrants. It works by binding bile acids in your intestines to form a product that is removed from the body. Read more on
www.nlm.nih.gov
Welchol
Colesevelam is used to lower high cholesterol levels in the blood. This may help prevent medical problems caused by cholesterol clogging the blood vessels. This medicine is also used to treat high blood sugar levels for patients with type 2 diabetes . Read more on
www.mayoclinic.com
Welchol
WelChol is used to lower blood cholesterol levels when diet and exercise prove insufficient. It works by binding with cholesterol-based bile acids to take them out of circulation. This prompts the liver to produce a replacement supply of bile acids, drawing the extra cholesterol it needs out of the bloodstream. Read more on
www.pdrhealth.com
Colesevelam - Wikipedia, the free encyclopedia
Colesevelam is a bile acid sequestrant administered orally. It is developed by Genzyme and marketed in the US by Daiichi Sankyo under the brand name WelChol ... Read more on
en.wikipedia.org
Welchol (Colesevelam Hcl) Drug Information: User Reviews, Side ...
Learn about the prescription medication Welchol (Colesevelam Hcl), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient ... Read more on
www.rxlist.com
COLESEVELAM - ORAL (Welchol) side effects, medical uses, and drug ...
Mar 11, 2011 ... Consumer information about the medication COLESEVELAM - ORAL (Welchol), ... Read more about the prescription drug COLESEVELAM - ORAL. Read more on
www.medicinenet.com
Welchol (colesevelam) medical facts from Drugs.com
Dec 15, 2010 ... Physician reviewed Welchol patient information - includes Welchol description, dosage and directions. Read more on
www.drugs.com
Welchol (colesevelam) Drug Side Effects, Interactions, and ...
Drug information on Welchol (colesevelam), includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what to ... Read more on
www.emedicinehealth.com
Colesevelam hydrochloride.
by KL Steinmetz - 2002 - Cited by 39 - Related articles Read more on
scholar.google.com
Contents
Description and Clinical Pharmacology
WELCHOL (colesevelam hydrochloride) is a non-absorbed, polymeric, lipid-lowering and glucose-lowering agent intended for oral administration. Colesevelam hydrochloride is a high-capacity bile acid-binding molecule.
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www.druglib.com
Drug Interactions, Overdosage and Contraindications
Doses of WELCHOL in excess of 4.5 g/day have not been tested. Because WELCHOL is not absorbed, the risk of systemic toxicity is low. However, excessive doses of WELCHOL may cause more severe local gastrointestinal effects (e.g., constipation) than recommended doses.
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www.druglib.com
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
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www.nlm.nih.gov
Indications and Dosage
WELCHOL is indicated as an adjunct to diet and exercise to reduce elevated low-density lipoprotein cholesterol (LDL-C) in patients with primary hyperlipidemia (Fredrickson Type IIa) as monotherapy or in combination with an hydroxymethyl-glutaryl-coenzyme A (HMG CoA) reductase inhibitor. Lipid-altering agents should be used in addition to a diet restricted in saturated fat and cholesterol when response to diet and non-pharmacological interventions alone has been inadequate [See Clinical Studies...
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www.druglib.com
Medicine storage
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
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www.nlm.nih.gov
Missed dose
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed dose.
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www.nlm.nih.gov
Other information
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to colesevelam.
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www.nlm.nih.gov
Other uses for this medicine
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
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www.nlm.nih.gov
Precautions
Your doctor will want to check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it .
Read more on
www.mayoclinic.com
Proper use
Colesevelam comes as a tablet to take by mouth. It is usually taken once or twice a day with meals and a beverage. Your doctor will tell you how many tablets to take at each dose. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take colesevelam exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
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www.nlm.nih.gov
Proper Use
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Read more on
www.mayoclinic.com
Side Effects and Adverse Reactions
Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in clinical studies of another drug and may not reflect the rates observed in practice.
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Special diatery instructions
Eat a low-cholesterol, low-fat diet, which includes cottage cheese, fat-free milk, fish, vegetables, poultry, and egg whites. Use monounsaturated oils such as olive, peanut, and canola oils or polyunsaturated oils such as corn, safflower, soy, sunflower, cottonseed, and soybean oils. Avoid foods with excess fat in them such as meat (especially liver and fatty meat), egg yolks, whole milk, cream, butter, shortening, pastries, cakes, cookies, gravy, peanut butter, chocolate, olives, potato chips,...
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www.nlm.nih.gov
Special precautions
Before taking colesevelam,tell your doctor and pharmacist if you are allergic to colesevelam or any other medications..
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www.nlm.nih.gov
Summary
WelChol contains colesevelam hydrochloride (hereafter referred to as colesevelam), a non-absorbed, polymeric, lipid-lowering agent intended for oral administration. Colesevelam is a high capacity bile acid binding molecule. Colesevelam is poly (allylamine hydrochloride) cross-linked with epichlorohydrin and alkylated with 1-bromodecane and (6-bromohexyl)-trimethylammonium bromide. Colesevelam is hydrophilic, and insoluble in water.
Read more on
www.druglib.com
Uses
Colesevelam is used along with diet, weight loss, and exerciseto reduce the amount of cholesterol and certain fatty substances in the blood. Colesevelam may be used alone or in combination with other cholesterol-lowering medications known as statins (atorvastatin [Lipitor], cerivastatin [Baycol], lovastatin [Mevacor], pravastatin [Pravachol], or simvastatin [Zocor]). Colesevelam is also used to control blood sugar levels in patients with type 2 diabetes (condition in which the body does not...
Read more on
www.nlm.nih.gov