What is diabetic nephropathy?

The exact cause of diabetic nephropathy is unknown, but it is believed that uncontrolled high blood sugar leads to the development of kidney damage, especially when high blood pressure is also present. In some cases, your genes or family history may also play a role. Not all persons with diabetes develop this condition.

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Also known as Diabetic Kidney Disease, Diabetic Nephropathies, nephropathy - diabetic, diabetic kidney problems, Diabetic Glomerulosclerosis, Kimmelstiel-Wilson Syndrome, Kimmelstiel Wilson Disease, Kimmelstiel-Wilson Disease, Nodular Glomerulosclerosis, Kimmelstiel Wilson Syndrome, Diabetic Kidney Diseases, Intracapillary Glomerulosclerosis
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Diabetic Nephropathy

Diabetic nephropathy is kidney disease or damage that results as a complication of diabetes. See also: Type 1 diabetes Type 2 diabetes Risk factors for diabetes Chronic kidney disease

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IgA nephropathy

IgA nephropathy also called Berger's disease is a common kidney disease that occurs when an antibody called IgA lodges in your kidneys. This hampers your kidneys' ability to filter waste and excess water from your blood. Over time, IgA nephropathy can lead to blood and protein in your urine, high blood pressure, and swollen hands and feet.

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Treats a dry, irritated cough caused by the flu or the common cold.

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Diabetic Ketoacidosis

Diabetic ketoacidosis (DKA) is a state of inadequate insulin levels resulting in high blood sugar and accumulation of organic acids and ketones in the blood. It is also common in DKA to have severe dehydration and significant alterations of the bodys blood chemistry. DKA is usually seen in people who have type 1 (insulin-dependent) diabetes. Most often, these are diabetics younger than 25 years, but the condition may occur in diabetics of any age. Males and females are equally affected.

Diabetic nephropathy - Wikipedia, the free encyclopedia

Diabetic nephropathy (nephropatia diabetica), also known as Kimmelstiel-Wilson syndrome, or nodular diabetic glomerulosclerosis and intercapillary ...

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Diabetic Nephropathy: eMedicine Endocrinology

Nov 19, 2009 ... Overview: Diabetes is a metabolic disorder of multiple causes characterized by chronic hyperglycemia and disorders of carbohydrate, fat, ...

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Diabetic Nephropathy

Jan 1, 2009 ... Diabetic Nephropathy Online Medical Reference - from definition and diagnosis through risk factors and treatments. Co-authored by Saud Butt, ...

Diabetic Nephropathy Overview - Diabetic Nephropathy - Nephrology ...

May 1, 2010 ... Diabetic nephropathy is kidney disease that develops as a result of diabetes mellitus (DM). Diabetes is the most common cause of kidney ...

Diabetic Nephropathy -- familydoctor.org

Learn about the symptoms, diagnosis and treatment of diabetic nephropathy, or kidney damage caused by diabetes.

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Kidney Disease (Nephropathy) - American Diabetes Association

Diabetes can damage the kidneys and cause them to fail. Failing kidneys lose their ability to filter out waste products, resulting in kidney disease. ...

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Exams and Tests
The main sign of diabetic nephropathy is persistent protein in the urine. (Protein may appear in the urine for 5 to 10 years before other symptoms develop.) If your doctor thinks you might have this condition, a microalbuminuria test will be done. A positive test often means you have at least some damage to the kidney from diabetes. Damage at this stage may be reversible. The test results can be high for other reasons, so it needs to be repeated for confirmation.

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Medical advice
Call your health care provider if you have diabetes and a routine urinalysis shows protein.

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Outlook (Prognosis)
Nephropathy is a major cause of sickness and death in persons with diabetes. It is the leading cause of long-term kidney failure and end-stage kidney disease in the United States, and often leads to the need for dialysis or kidney transplantation.

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Possible Complications
Possible complications include:Anemia; Chronic kidney failure (rapidly gets worse); Dialysis complications; End-stage kidney disease ; Hyperkalemia ; Severe hypertension ; Hypoglycemia ; Infections; Kidney transplant complications; Peritonitis (if peritoneal dialysis used)

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All persons with diabetes should have a yearly checkup with their doctor to have their blood and urine tested for signs of possible kidney problems.

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Early stage diabetic nephropathy has no symptoms. Over time, the kidney's ability to function starts to decline. Symptoms develop late in the disease and may include: Fatigue ; Foamy appearance or excessive frothing of the urine; Frequent hiccups ; General ill feeling ; Generalized itching; Headache ; Nausea and vomiting ; Poor appetite ; Swelling of the legs ; Swelling, usually around the eyes in the mornings; general body swelling may occur with late-stage disease; Unintentional weight gain...

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The goals of treatment are to keep the kidney disease from getting worse and prevent complications. This involves keeping your blood pressure under control (under 130/80). Controlling high blood pressure is the most effective way of slowing kidney damage from diabetic nephropathy. Your doctor may prescribe the following medicines to lower your blood pressure and protect your kidneys from damage: Angiotensin-converting enzyme (ACE) inhibitors, Angiotensin receptor blockers (ARBs). These drugs...

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