What is Flexeril?

Flexeril information from trusted sources:

Cyclobenzaprine

Cyclobenzaprine HCl relieves skeletal muscle spasm of local origin without interfering with muscle function.

Amrix

Cyclobenzaprine is used to help relax certain muscles in your body. It helps relieve the pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem. Cyclobenzaprine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of this medicine's side effects.

Flexeril

Flexeril is a muscle relaxant prescribed to relieve muscle spasms resulting from injuries such as sprains, strains, or pulls. Combined with rest and physical therapy, Flexeril provides relief of muscular stiffness and pain.

Cyclobenzaprine

Pharmacologic similarities among the tricyclic drugs require that certain withdrawal symptoms be considered when FLEXERIL is administered, even though they have not been reported to occur with this drug. Abrupt cessation of treatment after prolonged administration rarely may produce nausea, headache, and malaise. These are not indicative of addiction.

Cyclobenzaprine

FLEXERIL may have life-threatening interactions with MAO inhibitors. (See CONTRAINDICATIONS.)

Cyclobenzaprine

Incidence of most common adverse reactions in the 2 double-blind [ Note: FLEXERIL 10 mg data are from one clinical trial. FLEXERIL 5 mg and placebo data are from two studies. ] , placebo-controlled 5 mg studies (incidence of > 3% on FLEXERIL 5 mg): FLEXERIL 5 mgN=464, FLEXERIL 10 mgN=249, PlaceboN=469, Drowsiness, 29%, 38%, 10%, Dry Mouth, 21%, 32%, 7%, Fatigue, 6%, 6%, 3%, Headache, 5%, 5%, 8%,

Cyclobenzaprine

Cyclobenzaprine is closely related to the tricyclic antidepressants, e.g., amitriptyline and imipramine. In short term studies for indications other than muscle spasm associated with acute musculoskeletal conditions, and usually at doses somewhat greater than those recommended for skeletal muscle spasm, some of the more serious central nervous system reactions noted with the tricyclic antidepressants have occurred (see WARNINGS, below, and ADVERSE REACTIONS).