fragilexsyndrome

What is fragile x syndrome?


Fragile X syndrome is caused by a change in the FMR1 gene. A small section of the gene code (three letters only -- CGG) is repeated on a fragile area of the X chromosome. The more repeats, the more likely there is to be a problem.

Read more on www.nlm.nih.gov
Also known as fraxa, Martin-Bell Syndrome, Martin Bell Syndrome, marker x syndrome, Fragile X Syndromes, FRAXA Syndrome, FRAXE Syndrome, FRAXE Syndromes, FRAXA Syndromes
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fragile x syndrome information from trusted sources:

FRAXA

Fragile X syndrome is the most common form of inherited mental retardation. A problem with a specific gene causes the disease. Normally, the gene makes a protein you need for brain development. But the mutation causes a person to make little or none of the protein, which results in the symptoms of Fragile X. People with only a small change in the gene might not show any signs of Fragile X. People with bigger changes can have severe symptoms. These might include

Read more on www.nlm.nih.gov

Dysmetabolic Syndrome

The term metabolic syndrome is well recognized in the medical literature and in the lay press as well. Metabolic syndrome (also referred to as syndrome X or dysmetabolic syndrome) refers to an association between certain metabolic disorders and cardiovascular disease. While the criteria for the diagnosis vary, the concept of a clustering of risks factors that lead to cardiovascular disease is well accepted.

Metabolic syndrome

Metabolic syndrome is a cluster of conditions increased blood pressure, elevated insulin levels, excess body fat around the waist or abnormal cholesterol levels that occur together, increasing your risk of heart disease, stroke and diabetes.

Read more on www.mayoclinic.com

Cefotaxime

C16H16N5NaO7S2 M.W. 477.45... ... Treatment Cefotaxime for injection is indicated for the treatment of patients with serious infections caused by susceptible strains of the designated microorganisms in the diseases listed below. (1) Lower respiratory tract infections, including pneumonia, caused by Streptococcus pneumoniae (formerly Diplococcus pneumoniae), Streptococcus pyogenes* (Group A streptococci) and other streptococci (excluding enterococci, e.g., Enterococcus faecalis), Staphylococcus aureus (penicillinase and non-penicillinase producing), Escherichia coli, Klebsiella species, Haemophilus influenzae (including ampicillin resist&shy,ant strains), Haemophilus parainfluenzae, Proteus mirabilis, Serratia marcescens*, Enterobacter species, indole positive Proteus and Pseudomonas species (including P. aeruginosa). (2) Genitourinary infections. Urinary tract infections caused by Enterococcus species, Staphylococcus epidermidis, Staphylococcus aureus*, (penicillinase and non-penicillinase producing), Citrobacter species, Enterobacter species, Escherichia coli, Klebsiella species, Proteus mirabilis, Proteus vulgaris*, Providencia stuartii, Morganella morganii*, Providencia rettgeri*, Serratia marcescens and Pseudomonas species (including P. aeruginosa). Also, uncomplicated gonorrhea (cervical/urethral and rectal) caused by Neisseria gonorrhoeae, including peni&shy,cillinase producing strains. (3) Gynecologic infections, including pelvic inflammatory disease, endometritis and pelvic cellulitis caused by Staphylococcus epidermidis, Streptococcus species, Enterococcus species, Enterobacter species*, Klebsiella species*, Escherichia coli, Proteus mirabilis, Bacteroides species (including Bacteroides fragilis*), Clostridium species, and anaerobic cocci (including Peptostreptococcus species and Peptococcus species) and Fusobacterium species (including F. nucleatum*). Cefotaxime for injection, like other cephalosporins, has no activity against Chlamydia trachomatis....

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Pipracil

Therapeutic: PIPRACIL is indicated for the treatment of serious infections caused by susceptible strains of the designated microorganisms in the conditions listed below: Intra-Abdominal Infections including hepatobiliary and surgical infections caused by E. coli, Pseudomonas aeruginosa, enterococci, Clostridium spp., anaerobic cocci, or Bacteroides spp., including B. fragilis.

Read more on www.druglib.com

Citrus Bioflavonoids

Citrus Bioflavonoids are a class of flavonoids that include rutin, hesperidin, naringin, quercitin, and a standardized mixture of rutinosides known as hydroxyethylrutosides (HER). They are used for the treatment of capillary fragility (easy bruising) and venous insufficiency (varicose veins, hemorrhoids, diabetic vascular disease, and diabetic retinopathy).

Read more on www.pdrhealth.com

The National Fragile X Foundation

Jan 4, 2011 ... The National Fragile X Foundation unites the fragile X community to enrich ... toward improved treatments and a cure for fragile X syndrome.

Read more on www.nfxf.org

Fragile X syndrome - Wikipedia, the free encyclopedia

Fragile X syndrome (FXS), or Martin–Bell syndrome, is a genetic syndrome which results in a spectrum of characteristic physical and intellectual limitations ...

Read more on en.wikipedia.org

Fragile X Syndrome (FXS) Causes, Signs, Symptoms, and Treatments ...

Mar 12, 2011 ... Fragile X syndrome (also called Fragile X) is the most common inherited ... Symptoms of Fragile X syndrome occur because the mutated gene ...

Read more on www.medicinenet.com

Fragile X Syndrome

Mar 24, 2010 ... For more specific information about symptoms, check out the What are the Signs and Symptoms of Fragile X Syndrome? section of the NICHD ...

Read more on www.nichd.nih.gov

Contents

Exams and Tests
The person will have a family history of Fragile X syndrome (especially a male relative).

Read more on www.nlm.nih.gov
Medical advice
Call your health care provider if you suspect Fragile X syndrome in a child with mental retardation. Genetic counseling is recommended to help families understand the condition, and to understand the complex nature of DNA testing in Fragile X.

Read more on www.nlm.nih.gov
Outlook (Prognosis)
The outcome depends on the extent of mental retardation.

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Possible Complications
Complications vary depending on the type and severity of symptoms.

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Prevention
Genetic counseling may help both existing and prospective parents with a family history of Fragile X syndrome, or a family history of other symptoms such as tremor. Genetic testing can help determine the level of risk in these families.

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Support Groups
National Fragile X Foundation -- www.nfxf.org

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Symptoms
Family members who have fewer repeats in the FMR1 gene may not have mental retardation, but may have other problems. Women with less severe changes may have premature menopause or difficulty becoming pregnant. Both men and women may have problems with tremors and poor coordination.

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Treatment
There is no specific treatment for Fragile X syndrome. Instead, training and education help affected children function at as high a level as possible. Because the condition is not rare, educational approaches have been developed and tested.

Read more on www.nlm.nih.gov