What is hematocrit increased?

Hematocrit is a blood test that measures the percentage of red blood cells found in whole blood. This measurement depends on the number of red blood cells and the size of red blood cells. The hematocrit is almost always ordered as part of a complete blood count.

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Bosentan is an endothelin receptor antagonist, belonging to a class of highly substituted pyrimidine derivatives, with no chiral centers. It is designated chemically as 4-tert-butyl-N-[6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-[2,2']-bipyrimidin-4-yl]- benzenesulfonamide monohydrate and has the following structural formula:Bosentan has a molecular weight of 569.64 and a molecular formula of C27H29N5O6S&bull,H2O. Bosentan is a white to yellowish powder. It is poorly soluble in water (1.0 mg/100 mL) and in aqueous solutions at low pH (0.1 mg/100 mL at pH 1.1 and 4.0, 0.2 mg/100 mL at pH 5.0). Solubility increases at higher pH values (43 mg/100 mL at pH 7.5). In the solid state, bosentan is very stable, is not hygroscopic and is not light sensitive. Tracleer is an endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension (WHO Group I) in patients with WHO Class II to IV symptoms to improve exercise capacity and decrease clinical worsening (1.1). 1.1 Pulmonary Arterial Hypertension 2. DOSAGE AND ADMINISTRATION 2.1 Recommended Dosing 2.2 Required Monitoring 2.3 Dosage Adjustments for Patients Developing Aminotransferase Elevations 2.4 Use in Females of Childbearing Potential 2.5 Use in Patients with Pre-existing Hepatic Impairment 2.6 Patients with Low Body Weight 2.7 Use with Ritonavir 2.8 Treatment Discontinuation 3. DOSAGE FORMS AND STRENGTHS 4. CONTRAINDICATIONS 4.1 Pregnancy Category X 4.2 Use with Cyclosporine A 4.3 Use with Glyburide 4.4 Hypersensitivity 5 WARNINGS AND PRECAUTIONS 5.1 Potential Liver Injury 5.2 Patients with Pre-existing Hepatic Impairment 5.3 Fluid Retention 5.4 Decreased Sperm Counts 5.5 Decreases in Hemoglobin and Hematocrit 5.6 Pulmonary Veno-Occlusive Disease 5.7 Prescribing and Distribution Program for Tracleer 6. ADVERSE REACTIONS 6.1 Clinical Studies Experience 6.2 Postmarketing Experience 7. DRUG INTERACTIONS 7.1 Cytochrome P450 Summary 7.2 Hormonal Contraceptives 7.3 Cyclosporine A 7.4 Glyburide 7.5...

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Hematocrit - Wikipedia, the free encyclopedia

Anabolic Androgenic Steroid (AAS) use can also increase the amount of RBCs and, therefore, impact the hematocrit, in particular the compounds boldenone and ...

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Hematocrit Blood Test on MedicineNet.com

Mar 16, 2011 ... Low or high hematocrit may signal conditions such as anemia, ... Diarrhea is an increase in the frequency of bowel movements or a decrease ...

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Normalization of hematocrit in hemodialysis patients with cardiac ...

by PJ Conlon - 2000 - Cited by 18 - Related articles

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Hematocrit influences postop outcomes | theheart.org

Jun 12, 2007 ... Results showed that 30-day mortality and cardiac-event rates increased with either positive or negative deviations from normal hematocrit ...

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changes, they note a higher rate ofane¬ tunityto respondto the ...

by MA Klebanoff - 1990

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hematocrit - definition of hematocrit in the Medical dictionary ...

An increase in the number or size of red cells increases the amount of space they occupy, resulting in a higher hematocrit. Thalassemia is a condition which ...

Effects Of A High Protein Diet On Rbc, Hemoglobin And Hematocrit ...

Effects Of A High Protein Diet On Rbc, Hemoglobin And Hematocrit. Red blood cells, hemoglobin and hematocrit are interrelated and are affected by protein ...

Read more on www.livestrong.com

Polycythemia, Secondary: eMedicine Hematology

Dec 17, 2009 ... Increased hemoglobin and hematocrit values reflect the ratio of red blood cell mass to plasma volume. Any change in either the hemoglobin or ...

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Blood Viscosity, Hematocrit Linked to Diabetes Risk

Dec 2, 2008 ... Elevated blood viscosity and hematocrit are associated with an increased risk of insulin resistance and type 2 diabetes, according to a new ...


The complete blood count (CBC) is one of the most commonly ordered blood tests by doctors. To understand this test, it is important to know that the blood generally consists of two major parts, plasma and cellular elements. The plasma is the part of the blood that is liquid which allows the blood to flow easily. The other part of the blood consists of blood cells or cellular elements.

If your doctor suspects that you have anemia, polycythemia, or dehydration

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Hematocrit test
Hematocrit (he-MAT-uh-krit) is the proportion of your blood composed of red blood cells. Hematocrit (Hct) is also called packed-cell volume (PCV).

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Erythropoietin is a glycoprotein which stimulates red blood cell production. It is produced in the kidney and stimulates the division and differentiation of committed erythroid progenitors in the bone marrow. EPOGEN (Epoetin alfa), a 165 amino acid glycoprotein manufactured by recombinant DNA technology, has the same biological effects as endogenous erythropoietin.1 It has a molecular weight of 30,400 daltons and is produced by mammalian cells into which the human erythropoietin gene has been introduced. The product contains the identical amino acid sequence of isolated natural erythropoietin. Treatment of Anemia of Chronic Renal Failure Patients EPOGEN is indicated for the treatment of anemia associated with CRF, including patients on dialysis and patients not on dialysis. EPOGEN is indicated to elevate or maintain the red blood cell level (as manifested by the hematocrit or hemoglobin determinations) and to decrease the need for transfusions in these patients.

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Ferritin test
You may have a ferritin test for several reasons: To diagnose a medical condition. Your doctor may suggest a ferritin test if other blood tests have shown that the level of oxygen-carrying protein in your red blood cells (hemoglobin) is low, or if the proportion of red blood cells to the fluid component in your blood (hematocrit) is low. These may indicate that you have iron deficiency anemia. A ferritin test can help confirm that diagnosis. A ferritin test may also be used to help diagnose conditions such as hemochromatosis, liver disease and adult Still's disease, among others. When used to diagnose a medical condition, a ferritin test is often done in conjunction with an iron test and a total iron-binding capacity (TIBC) and transferrin test. These tests provide additional information about how much iron is in your body., To monitor a medical condition. If you've been diagnosed with a disorder that results in too much iron in your body, such as hemochromatosis or hemosiderosis, your doctor may use a ferritin test to monitor your condition and guide treatment.

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Mallory-Weiss tear
CBC possibly showing low hematocrit EGD (esophagogastroduodenoscopy) showing a tear with bleeding

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Iron deficiency anemia
Fecal occult blood test Hematocrit and hemoglobin (red blood cell measures) Iron binding capacity (TIBC) in the blood RBC indices Serum ferritin Serum iron level

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A complete blood count (CBC) test measures the following: The number of red blood cells (RBCs) The number of white blood cells (WBCs) The total amount of hemoglobin in the blood The fraction of the blood composed of red blood cells (hematocrit) The size of the red blood cells (mean corpuscular volume, or MCV) The CBC test also provides specific information the size and hemoglobin content of individual red blood cells. This is determined from the additional following measurements: Mean corpuscular hemoglobin (MCH) Mean corpuscular hemoglobin concentration (MCHC) The platelet count is also usually included in the CBC. See also: Red blood cell (RBC) count White blood cell (WBC) count

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Doctors diagnose anemia with the help of a medical history, a physical exam and blood tests, including a complete blood count (CBC). This blood test measures levels of the red blood cells contained in the blood (hematocrit) and the hemoglobin in your blood. Normal adult hematocrit values are between 32 and 43 percent. Normal adult hemoglobin values are generally in the 11 to 15 grams per deciliter range.

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PROCRIT is indicated for the treatment of anemia associated with CRF, including patients on dialysis (ESRD) and patients not on dialysis. PROCRIT is indicated to elevate or maintain the red blood cell level (as manifested by the hematocrit or hemoglobin determinations) and to decrease the need for transfusions in these patients.

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Angiomax is not intended for intramuscular administration. Although most bleeding associated with the use of Angiomax in PTCA occurs at the site of arterial puncture, hemorrhage can occur at any site. An unexplained fall in blood pressure or hematocrit, or any unexplained symptom, should lead to serious consideration of a hemorrhagic event and cessation of Angiomax administration.

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