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What is Lexapro?
Lexapro® (escitalopram oxalate) is an orally administered selective serotonin reuptake inhibitor (SSRI). Escitalopram is the pure S-enantiomer (single isomer) of the racemic bicyclic phthalane derivative citalopram. Escitalopram oxalate is designated S-(+)-1-[3-(dimethyl-amino)propyl]-1-(p -fluorophenyl)-5-phthalancarbonitrile oxalate with the following structural formula: The molecular formula is C20H21FN2O • C2H2O4 and the molecular weight is 414.40.
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Also known as Citalopram, Escitalopram, escitalopram oxalate, Cytalopram, Lu-10-171, Lu10171
Lexapro information from trusted sources:
Lexapro (escitalopram oxalate) - The Good, The Bad and The Funny ...
Users' perspectives on Lexapro(escitalopram oxalate): uses, pros & cons, effects , side effects and stuff doctors usually don't tell you. Read more on
www.crazymeds.us
Lexapro - Side Effects, Dosage, Interactions - Drugs ...
Lexapro - Escitalopram is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Escitalopram affects chemicals in ... Read more on
www.everydayhealth.com
Lexapro
Lexapro (escitalopram oxalate) is an orally administered selective serotonin reuptake inhibitor (SSRI). Escitalopram is the pure S-enantiomer (single isomer) of the racemic bicyclic phthalane derivative citalopram. Escitalopram oxalate is designated S-(+)-1-[3-(dimethyl-amino)propyl]-1-(p-fluorophenyl)-5-phthalancarbonitrile oxalate with the following structural formula:The molecular formula is C20H21FN2O &bull, C2H2O4 and the molecular weight is 414.40. Lexapro is a selective serotonin reuptake inhibitor (SSRI) indicated for: 1.1 Major Depressive Disorder 1.2 Generalized Anxiety Disorder 2 DOSAGE AND ADMINISTRATION 2.1 Major Depressive Disorder 2.2 Generalized Anxiety Disorder 2.3 Special Populations 2.4 Discontinuation of Treatment with Lexapro 2.5 Switching Patients To or From a Monoamine Oxidase Inhibitor 3 DOSAGE FORMS AND STRENGTHS 3.1 Tablets 3.2 Oral Solution 4 CONTRAINDICATIONS 4.1 Monoamine oxidase inhibitors (MAOIs) 4.2 Pimozide 4.3 Hypersensitivity to escitalopram or citalopram 5 WARNINGS AND PRECAUTIONS 5.1 Clinical Worsening and Suicide Risk 5.2 Serotonin Syndrome or Neuroleptic Malignant Syndrome (NMS)-like Reactions 5.3 Discontinuation of Treatment with Lexapro 5.4 Seizures 5.5 Activation of Mania/Hypomania 5.6 Hyponatremia 5.7 Abnormal Bleeding 5.8 Interference with Cognitive and Motor Performance 5.9 Use in Patients with Concomitant Illness 5.10 Potential for Interaction with Monoamine Oxidase Inhibitors 6 ADVERSE REACTIONS 6.1 Clinical Trials Experience 6.2 Post-Marketing Experience 7 DRUG INTERACTIONS 7.1 Serotonergic Drugs 7.2 Triptans 7.3 CNS Drugs 7.4 Alcohol 7.5 Monoamine Oxidase Inhibitors (MAOIs) 7.6 Drugs That Interfere With Hemostasis (NSAIDs, Aspirin, Warfarin, etc.) 7.7 Cimetidine 7.8 Digoxin 7.9 Lithium 7.10 Pimozide and Celexa 7.11 Sumatriptan 7.12 Theophylline 7.13 Warfarin 7.14 Carbamazepine 7.15 Triazolam 7.16 Ketoconazole 7.17 Ritonavir 7.18 CYP3A4 and -2C19 Inhibitors 7.19 Drugs Metabolized by Cytochrome P4502D6 7.20 Metoprolol... Read more on
dailymed.nlm.nih.gov
Generic Lexapro Coming to Stores Near You! | World of Psychology
Feb 12, 2007 ... The first generic version of Lexapro, one of the most widely prescribed antidepressants, with more than $2 billion in sales last year, ... Read more on
psychcentral.com
Escitalopram - Wikipedia, the free encyclopedia
Escitalopram (trade names Lexapro, Cipralex, Seroplex, Lexamil, Lexam) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. ... Read more on
en.wikipedia.org
Lexapro Information from Drugs.com
Lexapro (escitalopram) is used to treat anxiety and major depressive disorder. Includes Lexapro side effects, interactions and indications. Read more on
www.drugs.com
Lexapro and Pramipexole and to Treat Major Depression - Full Text ...
Jun 29, 2004 ... This study compares the effectiveness of the combination of antidepressants: Lexapro and Pramipexole, with the effectiveness of each ... Read more on
clinicaltrials.gov
Contents
Brand Names and Description
Escitalopram is used to treat mental depression and generalized anxiety disorder (GAD).
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www.mayoclinic.com
Drug Interactions, Overdosage and Contraindications
In clinical trials of escitalopram, there were reports of escitalopram overdose, including overdoses of up to 600 mg, with no associated fatalities. During the postmarketing evaluation of escitalopram, Lexapro overdoses involving overdoses of over 1000 mg have been reported. As with other SSRIs, a fatal outcome in a patient who has taken an overdose of escitalopram has been rarely reported.
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FDA Alerts
FDA Alerts: Persistent Pulmonary Hypertension [issued 7/2006] The results of a study that looked at the use of antidepressant medicines during pregnancy in mothers of babies born with a serious condition called persistent pulmonary hypertension of the newborn (PPHN) were recently published in a medical journal... More about this FDA Alert SSRIs/SNRI/Triptan and Serotonin Syndrome [issued 7/2006] A life-threatening condition called serotonin syndrome can happen when medicines called selective...
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Indications and Dosage
Lexapro (escitalopram) is indicated for the acute and maintenance treatment of major depressive disorder in adults and in adolescents 12 to 17 years of age [ see Clinical Studies (14.1) ].
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Other Rx Information
Animal studies suggest that the abuse liability of racemic citalopram is low. Lexapro has not been systematically studied in humans for its potential for abuse, tolerance, or physical dependence. The premarketing clinical experience with Lexapro did not reveal any drug-seeking behavior. However, these observations were not systematic and it is not possible to predict on the basis of this limited experience the extent to which a CNS-active drug will be misused, diverted, and/or abused once marketed....
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Precautions
It is very important that your doctor check you or your child's progress at regular visits to allow for changes in your dose and to help reduce any side effects.
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www.mayoclinic.com
Proper Use
Take this medicine only as directed by your doctor to help your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
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www.mayoclinic.com
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
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www.mayoclinic.com
Summary
Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of Lexapro or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo...
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