metastaticbreastcancer

What is metastatic breast cancer?


What are they Multiparameter gene expression tests for breast cancer evaluate specific groups of genes in malignant tumor tissue in order to predict prognosis, recurrence, and metastasis of the cancer, as well as to guide treatment. These tests are ultimately aimed at developing a personalized approach to patient care. Cancers represent uncontrolled growth of abnormal cells. Each breast cancer has its own genetic makeup that is distinct from the normal tissue surrounding it. Genes in the tumor regulate how rapidly it will grow, its likelihood of metastasizing and moving throughout the body, whether or not its growth is supported by estrogen or progesterone, whether it over-expresses certain proteins such as Her-2/neu, and how responsive it will be to different treatments. Regulation of tumor genes is accomplished through gene expression &ndash, the timing and quantity of production of gene-specific ribonucleic acid (RNA) and proteins. Gene expression patterns include both the increase and/or decrease in the expression of genes (upregulation and downregulation) that are responsible for the production of proteins. Multiparameter gene expression tests measure the products of multiple tumor genes at the same time. The result is a pattern of gene expressions that are consolidated into a score. The score is then used to help predict the likely behavior of the tumor.

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metastatic breast cancer information from trusted sources:

Breast Cancer

Breast cancer is cancer arising in breast tissue. Cancer is simply a group of abnormal cells that have abnormal growth patterns.

Breast Cancer

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Read more on www.mayoclinic.com

Breast Cancer

Breast cancer is the most common cancer among women. Estimates indicate that 212,290 American women will be diagnosed with breast cancer in 2006, and about 41,000 women will die annually from this disease. It is estimated that 12% of American women will develop the disease and 3.5% will die from it.

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Metastatic breast cancer - Wikipedia, the free encyclopedia

Metastatic breast cancer is a complex multi-step process involving the expansion of cancerous cells from the breast to other areas of the body. ...

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Metastatic Breast Cancer - Breast Cancer Statistics - Breast ...

Nov 26, 2007 ... Metastatic breast cancer is diagnosed when cells from the original breast tumor have spread beyond your breast to other parts of your body.

Read more on breastcancer.about.com

Metastatic Breast Cancer

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Treatment of metastatic breast cancer

Oct 6, 2010 ... Metastatic breast cancer is usually not a curable condition. However, treatment can prolong life, delay the progression of the cancer, ...

Read more on www.uptodate.com

Dermatologic Manifestations of Metastatic Carcinoma of the Skin ...

Mar 2, 2010 ... Because breast cancer is so common, cutaneous metastasis of breast ... Occasionally, patients with metastatic breast cancer may have a firm, ...

Read more on emedicine.medscape.com

Herceptin Metastatic Breast Cancer Treatment - Cancer Information ...

Mar 14, 2011 ... December 1998 -- Herceptin (trastuzumab) is the newest drug for the management of metastatic breast cancer (breast cancer that has spread ...

Read more on www.medicinenet.com

Living with metastatic breast cancer (August 2010) - Susan G ...

Metastatic breast cancer (also called advanced or stage IV breast cancer ) is breast cancer that has spread beyond the breast and nearby lymph nodes to ...

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Contents

Cancer
Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body. Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the cancer type and how advanced it is. Treatment plans may include surgery, radiation and/or chemotherapy.

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Breast Cancer
The main symptom of breast cancer is usually a lump or thickened area of tissue in your breast. Most breast lumps are found by the women who have them and it is very important to be aware of any lumps or changes in the appearance, feel or shape of your breasts. The sooner a cancerous lump is detected, the better the chances of treating it successfully.

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Metastatic cancer to the lung
Metastatic tumors in the lungs are cancers that developed at other sites and spread through the bloodstream or lymphatic system to the lungs. Common tumors that spread to the lungs include: Bladder cancer , Breast cancer , Colon cancer , Neuroblastoma , Prostate cancer , Sarcoma, Wilm's tumor

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Male breast cancer
Male breast cancer is rare. It happens most often to men between the ages of 60 and 70. Risk factors for male breast cancer include exposure to radiation, a family history of breast cancer and having high estrogen levels, which can occur with diseases like cirrhosis or Klinefelter's syndrome. Symptoms of male breast cancer include lumps, changes to the nipple or breast skin, or discharge of fluid from the nipple. Treatment for male breast cancer is usually a mastectomy, which is surgery to remove the breast. Other treatments include radiation, chemotherapy and/or hormone therapy.

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Breast Cancer Gene 1 and Breast Cancer Gene 2
To assess the risk of developing breast or ovarian cancer associated with inheriting mutations in the BRCA-1 or BRCA-2 genes

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Inflammatory breast cancer
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BRCA gene test for breast cancer
The BRCA gene test is a blood test that uses DNA analysis to identify changes (mutations) in either one of two breast cancer susceptibility genes known as BRCA1 or BRCA2. Genetic counseling also is part of the BRCA gene test process. After having a BRCA gene test performed, you learn whether you carry an inherited BRCA gene mutation and receive an estimate of your personal risk of breast cancer and ovarian cancer.

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Advanced (Metastatic) Breast Cancer | Breast Health Resource ...
The term, metastatic, describes a cancer that has spread to distant organs from the original tumor site. Metastatic breast cancer is the most advanced stage ...

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Recurrent and Metastatic Breast Cancer
Nov 26, 2008 ... We know you really don't want to be here, reading about breast cancer recurrence or metastasis. If you've had breast cancer, the possibility ...

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Metastatic Cancer: Q&A - National Cancer Institute
In this case, the disease in the lungs is metastatic breast cancer (not lung cancer). Under a microscope, metastatic breast cancer cells generally look the ...

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Metastatic Breast Cancer as a Chronic Condition
For women whose breast cancer has spread, treatments can improve their condition and add years to their life.

Read more on www.webmd.com