packedredbloodcells

What is packed red blood cells?


To determine if red blood cells, white blood cells, and platelets are normal in appearance and number, to distinguish between different types of white blood cells and to determine their relative percentages in the blood, to help diagnose a range of deficiencies, diseases, and disorders involving blood cell production, function, and destruction, to monitor cell production and cell maturity in diseases such as leukemia, during chemo/radiation therapy, or in the evaluation for hemoglobin variants

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Sickle cell anemia

Sickle cell anemia is an inherited form of anemia a condition in which there aren't enough healthy red blood cells to carry adequate oxygen throughout your body.

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Sickle cell anemia

Sickle cell anemia is a type of anemia named after a characteristic change in shape that occurs in the red blood cells. Anemia is a condition in which people do not have enough red blood cells. Red blood cells carry oxygen to body tissues with the help of a protein called hemoglobin. Normal red blood cells are circular, like a doughnut, and flexible. The cells of patients with sickle cell anemia have high levels of an abnormal type of hemoglobin called hemoglobin S. Hemoglobin S causes red blood cells to stiffen into a sickle shape, which looks like a crescent moon. Sickled cells die in about 10 to 20 days, compared to 120 days for normal red blood cells. Anemia develops because the body can't replace the dying cells fast enough.

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Packed red blood cells - Wikipedia, the free encyclopedia

In transfusion medicine, packed packed red blood cells are red blood cells that have been separated from whole blood for transfusion purposes. ...

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Transfusion of aged packed red blood cells results in decreased ...

by LN Kiraly - 2009 - Cited by 13 - Related articles

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Blood Donation and Processing

Both whole blood and PRBC's can be stored for up to 42 days at 1 - 6 degrees C. ... Packed red blood cells (PRBC's). Leukocyte depleted RBC's: cryopreserved ...

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PACKED RED BLOOD CELL TRANSFUSION IN THE INTENSIVE CARE UNIT ...

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Use of red blood cells for transfusion

Aug 12, 2010 ... Transfusion of aged packed red blood cells results in decreased tissue oxygenation in critically injured trauma patients. ...

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Stem cell transplant

Stem cell transplantations are often required to treat conditions that have damaged the bone marrow which, as a result, is no longer able to produce normal blood cells. Any disruption to the production of blood cells can be very serious, particularly if...

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Rhophylac

Rhophylac is a sterile Rho(D) Immune Globulin Intravenous (Human) solution in a prefilled, ready to use syringe for either intravenous or intramuscular injection. One syringe contains at least 1500 IU (300 µg) of IgG antibodies to Rho(D) in a 2 mL solution, sufficient to suppress the immune response to at least 15 mL of Rh-positive red blood cells1. The product potency is expressed in international units by comparison to the World Health Organization (WHO) standard, which is also the US and...

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Cyanokit

Hydroxocobalamin, the active ingredient in Cyanokit, is cobinamide dihydroxide dihydrogen phosphate (ester), mono (inner salt), 3&prime,-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole. The drug substance is the hydroxylated active form of vitamin B12 and is a large molecule in which a trivalent cobalt ion is coordinated in four positions by a tetrapyrol (or corrin) ring. It is a hygroscopic, odorless, dark red, crystalline powder that is freely soluble in water and ethanol, and practically insoluble in acetone and diethyl ether. Hydroxocobalamin has a molecular weight of 1346.36 atomic mass units, an empirical formula of C62H89CoN13O15P and the following structural formula:Cyanokit (hydroxocobalamin for injection) 5 g is a cyanide antidote package which contains two colorless 250 mL glass vials, each of which contains 2.5 g dark red lyophilized hydroxocobalamin, pH adjusted with hydrochloric acid, two transfer spikes, one IV administration set, one quick use reference guide and one package insert. Cyanokit contains hydroxocobalamin, an antidote indicated for the treatment of known or suspected cyanide poisoning. (1.1) 1.1 Indication 1.2 Identifying Patients with Cyanide Poisoning 1.3 Use with Other Cyanide Antidotes 2 DOSAGE AND ADMINISTRATION 2.1 Recommended Dosing 2.2 Preparation of Solution for Infusion 2.3 Incompatability Information 2.4 Storage of Reconstituted Drug Product 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS 5.1 Emergency Patient Management 5.2 Allergic Reactions 5.3 Blood Pressure Increase 5.4 Use of Blood Cyanide Assay 5.5 Interference with Clinical Laboratory Evaluations 5.6 Photosensitivity 6 ADVERSE REACTIONS 6.1 Clinical Studies Experience 7 DRUG INTERACTIONS 8 USE IN SPECIFIC POPULATIONS 8.1 Pregnancy 8.2 Labor and Delivery 8.3 Nursing Mothers 8.4 Pediatric Use 8.5 Geriatric Use 8.6 Renal Impairment 8.7 Hepatic Impairment 10 OVERDOSAGE 11 DESCRIPTION 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action...

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Contents

Sickle cell anemia
Sickle cell anemia is a disease passed down through families in which red blood cells form an abnormal crescent shape. (Red blood cells are normally shaped like a disc.)

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Renal Cell Cancer
The kidneys are a pair of organs located just above the waist on either side of the backbone. Their job is to filter excess water and waste products from the blood. The water and waste drain from each kidney through a tube called a ureter to the bladder and are eliminated from the body as urine. The kidneys also produce substances that help control blood pressure and formation of red blood cells. Several different types of cancer can develop in the kidney. Conventional or clear cell renal cell cancer, also known as renal cell carcinoma, is by far the most common type of kidney cancer in adults. Renes is the Latin word for kidney. Renal cell carcinoma accounts for about 85% of cancers arising from the kidney. Renal cell carcinoma develops in the tubules of the kidney, part of the filtering system.

CSF cell count
A CSF cell count is a test to measure the number of red and white blood cells that are in cerebrospinal fluid (CSF). CSF is a clear fluid that circulates in the space surrounding the spinal cord and brain.

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Stem cell transplant
A stem cell transplant is the infusion of healthy stem cells into your body. A stem cell transplant may be necessary if your bone marrow stops working and doesn't produce enough healthy stem cells. A stem cell transplant can help your body make enough healthy white blood cells, red blood cells or platelets, and reduce your risk of life-threatening infections, anemia and bleeding.

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Blood Cells
Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets. Red blood cells deliver oxygen from your lungs to your tissues and organs. White blood cells fight infection and are part of your body's defense system. Platelets help blood to clot. Bone marrow, the spongy material inside your bones, makes new blood cells. Blood cells constantly die and your body makes new ones. Red blood cells live about 120 days, platelets 6 days and white cells less than a day.

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red cell distribution width
The complete blood count (CBC) is one of the most commonly ordered blood tests by doctors. To understand this test, it is important to know that the blood generally consists of two major parts, plasma and cellular elements. The plasma is the part of the blood that is liquid which allows the blood to flow easily. The other part of the blood consists of blood cells or cellular elements.

Red Bood Cell Count
To evaluate any change in the number of red blood cells in your blood

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Red Blood Cell Antibody Identification
To identify the specific antibody present when a direct antiglobulin test (DAT) or indirect antiglobulin test (IAT) is positive, to help identify the cause of a transfusion reaction or the cause of hemolytic disease of the newborn (HDN)

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Low Red Blood Cell Count
Anemia describes the condition in which the number of red blood cells in the blood is low. For this reason, doctors sometimes describe someone with anemia as having a low blood count. A person who has anemia is called anemic.

Renal cell carcinoma
High blood pressure ( hypertension) High calcium level High red blood cell count Liver function abnormalities Spread of the cancer

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Red Cell Indices
MCV, MCH, MCHC, and RDW These are measurements or calculations related to red blood cells (RBCs) and are components of the Complete Blood Count (CBC), a commonly requested test used for a variety of purposes. To learn more about the CBC and these individual components, please review the CBC page, especially "The Test: How is it used" section.

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