quinine

What is quinine?


Qualaquin (quinine sulfate) is an antimalarial drug chemically described as cinchonan-9-ol, 6'-methoxy-, (8α, 9R)-, sulfate (2:1) (salt), dihydrate with a molecular formula of (C20H24N2O2)2•H2SO4•2H2O and a molecular weight of 782.96. The structural formula of quinine sulfate is: Quinine sulfate occurs as a white, crystalline powder that darkens on exposure to light. It is odorless and has a persistent very bitter taste. It is...

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quinine information from trusted sources:

Qualaquin

Qualaquin is supplied for oral administration as capsules containing 324 mg of the active ingredient quinine sulfate USP, equivalent to 269 mg free base.

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Quinine

Quinine is used alone or with other medications to treat malaria (a serious or life-threatening illness that is spread by mosquitos in certain parts of the world). Quinine should not be used to prevent malaria or to prevent or treat nighttime leg cramps. Quinine is in a class of medications called antimalarials. It works by killing the organisms that cause malaria.

Read more on www.nlm.nih.gov

Qualaquin

Quinine is used to treat malaria. This medicine usually is given with one or more other medicines for malaria.

Read more on www.mayoclinic.com

Qualaquin

Qualaquin (quinine sulfate) is an antimalarial drug chemically described as cinchonan-9-ol, 6'-methoxy-,(8α, 9R)-, sulfate (2:1) (salt), dihydrate with a molecular formula of (C20H24N2O2)2&bull,H2SO4&bull,2H2O and a molecular weight of 782.96. The structural formula of quinine sulfate is:Quinine sulfate occurs as a white, crystalline powder that darkens on exposure to light. It is odorless and has a persistent very bitter taste. It is only slightly soluble in water, alcohol, chloroform, and ether. Treatment of Malaria Qualaquin is indicated only for treatment of uncomplicated Plasmodium falciparum malaria. Quinine sulfate has been shown to be effective in geographical regions where resistance to chloroquine has been documented (See CLINICAL STUDIES).

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Quinine - Wikipedia, the free encyclopedia

Quinine is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and ...

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quinine medical facts from Drugs.com

Dec 15, 2010 ... Physician reviewed quinine patient information - includes quinine description, dosage and directions.

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Qualaquin (Quinine Sulfate Capsules) Drug Information: User ...

Learn about the prescription medication Qualaquin (Quinine Sulfate Capsules), drug uses, dosage, side effects, drug interactions, warnings, reviews and ...

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Quinine definition - Medical Dictionary definitions of popular ...

Mar 13, 2011 ... Quinine: The original antimalarial agent, quinine took its name from the Peruvian Indian word "kina" meaning "bark of the tree" referring to ...

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QUININE SULFATE (ANTIMALARIAL) - ORAL (Qualaquin) side effects ...

Mar 14, 2011 ... Consumer information about the medication QUININE SULFATE (ANTIMALARIAL) - ORAL (Qualaquin), includes side effects, drug interactions, ...

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QUININE SULFATE Q&As

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Contents

Brand Names and Description
Quinine is used to treat malaria. This medicine usually is given with one or more other medicines for malaria.

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Drug Interactions, Overdosage and Contraindications
Quinine undergoes hepatic metabolism primarily by CYP3A4 and to a lesser extent CYP1A2. In vivo drug interactions have been observed with drugs that induce or inhibit CYP3A4. Similarly, other in vivo drug interactions have been reported with drugs that inhibit or induce a wide range of CYP enzymes that may contribute to the metabolism of quinine such as CYP2C8, CYP2C9, CYP2C19, CYP2D6 and CYP2E1. Concomitant administration...

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In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

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Indications and Dosage
Qualaquin is indicated only for treatment of uncomplicated Plasmodium falciparum malaria. Quinine sulfate has been shown to be effective in geographical regions where resistance to chloroquine has been documented (See CLINICAL STUDIES).

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Medicine storage
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not refrigerate or freeze the medication. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

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Missed dose
Take the missed dose as soon as you remember it. However, if it has been more than 4 hours since the time you should have taken the missed dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

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Other Rx Information
Tolerance, abuse, or dependence with quinine sulfate has not been reported.

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Other uses for this medicine
Quinine is also sometimes used to treat babesiosis (a serious or life-threatening illness that is transmitted from animals to humans by ticks). Talk to your doctor about the risks of using this drug for your condition.

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Precautions
Quinine may cause blurred vision or a change in color vision. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not able to see well. If these reactions are especially bothersome, check with your doctor.

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Proper use
Quinine comes as a capsule to take by mouth. It usually is taken with food three times a day (every 8 hours) for 3-7 days. Take quinine at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take quinine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

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Proper Use
Take this medicine only as directed. Do not take more of it, do not take it more often, and do not take it for a longer time than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of side effects.

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Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

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Side Effects and Adverse Reactions
Quinine can adversely affect almost every body system. The most common adverse events associated with quinine use are a cluster of symptoms called "cinchonism", which occurs to some degree in almost all patients taking quinine. Symptoms of mild cinchonism include headache, vasodilation and sweating, nausea, tinnitus, hearing impairment, vertigo or dizziness, blurred vision, and disturbance in color perception. More severe symptoms of cinchonism are vomiting,...

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Special diatery instructions
Unless your doctor tells you otherwise, continue your normal diet.

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Special precautions
Before taking quinine,tell your doctor and pharmacist if you are allergic to quinine, quinidine, mefloquine (Lariam), or any other medications..

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Summary
Qualaquin is supplied for oral administration as capsules containing 324 mg of the active ingredient quinine sulfate USP, equivalent to 269 mg free base.

Read more on www.druglib.com
Uses
Quinine is used alone or with other medications to treat malaria (a serious or life-threatening illness that is spread by mosquitos in certain parts of the world). Quinine should not be used to prevent malaria or to prevent or treat nighttime leg cramps. Quinine is in a class of medications called antimalarials. It works by killing the organisms that cause malaria.

Read more on www.nlm.nih.gov