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What is rhabdomyolysis?
When muscle is damaged, a protein pigment called myoglobin is released into the bloodstream and filtered out of the body by the kidneys. Myoglobin breaks down into potentially harmful compounds. It may block the structures of the kidney, causing damage such as acute tubular necrosis or kidney failure.
Read more on www.nlm.nih.gov
Also known as skeletal muscle injury, Rhabdomyolyses, muscle injury, skeletal
rhabdomyolysis information from trusted sources:
Muscle Injury, Skeletal
Rhabdomyolysis describes the situation in which muscle in the body is damaged (rhabdomyo=skeletal muscle + lysis= rapid breakdown). There are a variety of types of muscle in the body, including: Read more on
www.emedicinehealth.com
Rhabdomyolysis
Rhabdomyolysis is the breakdown of muscle fibers resulting in the release of muscle fiber contents (myoglobin) into the bloodstream. Some of these are harmful to the kidney and frequently result in kidney damage. Read more on
www.nlm.nih.gov
Rhabdomyolysis
Rhabdomyolysis (rab-do-MI-oli-sis) is a condition where skeletal muscle cells die following an injury. Skeletal muscle cells are found in the muscles of your arms and legs. When muscle cells are injured, they break down and release large amounts of substances into the blood. This may include substances such as potassium, phosphate, creatinine kinase, and myoglobin. Potassium levels higher than normal are harmful to the heart. Myoglobin gives muscles their red color. It is normally passed in urine, but is harmful to the kidneys if large amounts are passed in the urine. Read more on
www.pdrhealth.com
Rhabdomyolysis - Wikipedia, the free encyclopedia
Rhabdomyolysis is a condition in which skeletal muscle (rhabdomyo) tissue breaks down rapidly (lysis) as a result to damage to the muscle. ... Read more on
en.wikipedia.org
Rhabdomyolysis Causes, Signs, Symptoms, and Treatment on ...
Mar 11, 2011 ... Rhabdomyolysis (RAB-DOE-MY-O-LIE-SIS) is the rapid destruction of skeletal muscle resulting in leakage into the urine of the muscle protein ... Read more on
www.medicinenet.com
Rhabdomyolysis in Emergency Medicine: eMedicine Emergency Medicine
Dec 6, 2010 ... Overview: Rhabdomyolysis was first described in the victims of crush injury during the 1940-1941 London, England, blitzkrieg bombing raids ... Read more on
emedicine.medscape.com
Rhabdomyolysis from statins: What's the risk? - MayoClinic.com
Rhabdomyolysis is a rare but potentially life-threatening side effect of statins. Read more on
www.mayoclinic.com
Rhabdomyolysis definition - Medical Dictionary definitions of ...
Mar 13, 2011 ... Our Rhabdomyolysis Main Article provides a comprehensive look at the who ... The key signs and symptoms of rhabdomyolysis include dark, red, ... Read more on
www.medterms.com
Rhabdomyolysis: Symptoms, Causes, and Treatments
Sep 14, 2010 ... Learn about rhabdomyolysis from WebMD. Get facts on symptoms, causes, and treatments of rhabdomyolysis. Read more on
www.webmd.com
Acute Exertional Rhabdomyolysis and Its Relationship to Sickle ...
by GL Harrelson - 1995 - Cited by 12 - Related articles Read more on
scholar.google.com
Contents
Exams and Tests
Medical advice
Call your health care provider if symptoms indicate rhabdomyolysis may be present.
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www.nlm.nih.gov
Outlook (Prognosis)
The outcome varies depending on the extent of kidney damage. Acute kidney failure occurs in many patients. Treatment soon after rhabdomyolysis begins will reduce the risk of chronic kidney damage.
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www.nlm.nih.gov
Possible Complications
Prevention
Drink plenty of fluids after strenous exercise to dilute the urine and flush the myoglobin out of the kidney. Proper hydration is also necessary after any condition or event that may involve damage to skeletal muscle.
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www.nlm.nih.gov
Symptoms
Abnormal urine color (dark, red, or cola colored) General weakness Muscle stiffness or aching (myalgia) Muscle tenderness Weakness of the affected muscles Additional symptoms that may be associated with this disease include the following: Fatigue Joint pain Seizures Weight gain (unintentional)
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www.nlm.nih.gov
Treatment
Early and aggressive fluids (hydration) may prevent kidney damage by rapidly flushing myoglobin out of the kidneys. Fluids may need to be given through a vein (by IV). Some patients may need kidney dialysis. Medicines that may be prescribed include diuretics and bicarbonate (if urine output is sufficient). Hyperkalemia and low blood calcium levels (hypocalcemia) should be treated if present. Kidney failure should be treated as appropriate.
Read more on
www.nlm.nih.gov