risperdal

What is Risperdal?


Risperidone is used to treat the symptoms of psychotic disorders, such as schizophrenia, mania or bipolar disorder, or irritability associated with autistic disorder. This medicine should NOT be used to treat behavioral problems in older adult patients who have dementia .

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Also known as risperidone
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Risperdal

RISPERDAL contains risperidone, a psychotropic agent belonging to the chemical class of benzisoxazole derivatives. The chemical designation is 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one. Its molecular formula is C23H27FN4O2 and its molecular weight is 410.49. The structural formula is:Risperidone is a white to slightly beige powder. It is practically insoluble in water, freely soluble in methylene chloride, and soluble in methanol and 0.1 N HCl. RISPERDAL is an atypical antipsychotic agent indicated for:...

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Risperdal

RISPERDAL(risperidone)TABLETS/ORAL SOLUTIONRISPERDAL M-TAB(risperidone)ORALLY DISINTEGRATING TABLETS

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Risperidone

Risperidone is used to treat the symptoms of psychotic disorders, such as schizophrenia, mania or bipolar disorder, or irritability associated with autistic disorder. This medicine should NOT be used to treat behavioral problems in older adult patients who have dementia .

Read more on www.mayoclinic.com

Risperdal

Risperdal is prescribed for the treatment of schizophrenia, a severe mental disorder that can cause delusions (false beliefs) and hallucinations. It is also used for the short-term treatment of mania associated with bipolar disorder. Risperdal is thought to work by muting the impact of dopamine and serotonin, two of the brain's key chemical messengers.

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Risperidone

Risperidone USP is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives. The chemical designation is 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-&shy,tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one. Its molecular formula is C23H27FN4O2 and its molecular weight is 410.49. The structural formula is:Risperidone is a white or almost white powder. It is practically insoluble in water, freely soluble in methylene chloride and sparingly soluble in alcohol. It dissolves in dilute acid solution. Risperidone is an atypical antipsychotic agent indicated for: 1.1 Schizophrenia 1.2 Bipolar Mania 1.3 Irritability Associated with Autistic Disorder 2 DOSAGE AND ADMINISTRATION 2.1 Schizophrenia 2.2 Bipolar Mania 2.3 Irritability Associated with Autistic Disorder &ndash, Pediatrics (Children and Adolescents) 2.4 Dosage in Special Populations 2.5 Co-Administration of Risperidone with Certain Other Medications 2.6 Administration of Risperidone Oral Solution 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS 5.1 Increased Mortality in Elderly Patients with Dementia-Related Psychosis 5.2 Cerebrovascular Adverse Events, Including Stroke, in Elderly Patients with Dementia-Related Psychosis 5.3 Neuroleptic Malignant Syndrome (NMS) 5.4 Tardive Dyskinesia 5.5 Hyperglycemia and Diabetes Mellitus 5.6 Hyperprolactinemia 5.7 Orthostatic Hypotension 5.8 Leukopenia, Neutropenia, and Agranulocytosis 5.9 Potential for Cognitive and Motor Impairment 5.10 Seizures 5.11 Dysphagia 5.12 Priapism 5.13 Body Temperature Regulation 5.14 Antiemetic Effect 5.15 Suicide 5.16 Use in Patients with Concomitant Illness 5.17 Monitoring: Laboratory Tests 6 ADVERSE REACTIONS 6.1 Commonly-Observed Adverse Reactions in Double-Blind, Placebo-Controlled Clinical Trials &ndash, Schizophrenia 6.2 Commonly-Observed Adverse Reactions in Double-Blind, Placebo-Controlled Clinical Trials &ndash, Bipolar Mania 6.3 Commonly-Observed Adverse Reactions...

Read more on dailymed.nlm.nih.gov

Risperidone

Risperidone Oral Solution contains risperidone, a psychotropic agent belonging to the chemical class of benzisoxazole derivatives. The chemical designation is 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one. Its molecular formula is C23H27FN4O2 and its molecular weight is 410.49. The structural formula is:Risperidone is a white to almost white powder. It is practically insoluble in water, freely soluble in methylene chloride, and soluble in methanol and 0.1 N HCl. Risperidone is an atypical antipsychotic agent indicated for: 1.1 Schizophrenia 1.2 Bipolar Mania 1.3 Irritability Associated with Autistic Disorder 2 DOSAGE AND ADMINISTRATION 2.1 Schizophrenia 2.2 Bipolar Mania 2.3 Irritability Associated with Autistic Disorder &ndash, Pediatrics (Children and Adolescents) 2.4 Dosage in Special Populations 2.5 Co-Administration of Risperidone with Certain Other Medications 2.6 Administration of Risperidone Oral Solution 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS 5.1 Increased Mortality in Elderly Patients with Dementia-Related Psychosis 5.2 Cerebrovascular Adverse Events, Including Stroke, in Elderly Patients with Dementia-Related Psychosis 5.3 Neuroleptic Malignant Syndrome (NMS) 5.4 Tardive Dyskinesia 5.5 Hyperglycemia and Diabetes Mellitus 5.6 Hyperprolactinemia 5.7 Orthostatic Hypotension 5.8 Leukopenia, Neutropenia, and Agranulocytosis 5.9 Potential for Cognitive and Motor Impairment 5.10 Seizures 5.11 Dysphagia 5.12 Priapism 5.13 Body Temperature Regulation 5.14 Antiemetic Effect 5.15 Suicide 5.16 Use in Patients with Concomitant Illness 5.17 Monitoring: Laboratory Tests 6 ADVERSE REACTIONS 6.1 Commonly-Observed Adverse Reactions in Double-Blind, Placebo-Controlled Clinical Trials &ndash, Schizophrenia 6.2 Commonly-Observed Adverse Reactions in Double-Blind, Placebo-Controlled Clinical Trials &ndash, Bipolar Mania 6.3 Commonly-Observed Adverse Reactions...

Read more on dailymed.nlm.nih.gov

Contents

Description and Clinical Pharmacology
RISPERDAL® (risperidone) is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives. The chemical designation is 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]- 6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one. Its molecular formula is C23H27FN4O2 and its molecular weight is 410.49. The structural formula is: Risperidone is a white to slightly beige powder. It is practically insoluble in water, freely soluble in methylene chloride, and...

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Drug Interactions, Overdosage and Contraindications
In a drug interaction study in schizophrenic patients, 11 subjects received risperidone titrated to 6 mg/day for 3 weeks, followed by concurrent administration of carbamazepine for an additional 3 weeks. During co-administration, the plasma concentrations of risperidone and its pharmacologically active metabolite, 9-hydroxyrisperidone, were decreased by about 50%. Plasma concentrations of carbamazepine did not appear to be affected. The dose of risperidone may need to be titrated accordingly...

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Indications and Dosage
The efficacy of RISPERDAL® in schizophrenia was established in short-term (6- to 8-weeks) controlled trials of schizophrenic inpatients (see CLINICAL PHARMACOLOGY).

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Other Rx Information
RISPERDAL® has not been systematically studied in animals or humans for its potential for abuse, tolerance, or physical dependence. While the clinical trials did not reveal any tendency for any drug-seeking behavior, these observations were not systematic and it is not possible to predict on the basis of this limited experience the extent to which a CNS-active drug will be misused, diverted, and/or abused once marketed. Consequently, patients should be evaluated carefully for a history...

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Precautions
Your doctor should check your progress at regular visits, especially during the first few months of treatment with this medicine. This will allow the dosage to be changed if necessary to meet your needs.

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Proper Use
Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more or less of it, do not take it more or less often, and do not take it for a longer or shorter time than your doctor ordered.

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Side Effects
Along with its needed effects, risperidone can sometimes cause serious side effects. Tardive dyskinesia (a movement disorder) may occur and may not go away after you stop using the medicine. Signs of tardive dyskinesia include fine, worm-like movements of the tongue, or other uncontrolled movements of the mouth, tongue, cheeks, jaw, or arms and legs. Other serious but rare side effects may also occur. These include neuroleptic malignant syndrome (NMS), which may cause severe muscle stiffness, fever, severe tiredness or weakness, fast heartbeat, difficult breathing, increased sweating, loss of bladder control, or seizures. You and your doctor should discuss the good this medicine will do as well as the risks of taking it.

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Summary
RISPERDAL®(risperidone)TABLETS/ORAL SOLUTIONRISPERDAL® M-TAB®(risperidone)ORALLY DISINTEGRATING TABLETS

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