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What is Seroquel?
Quetiapine is used to treat psychotic disorders, such as schizophrenia. It is also used to treat symptoms of bipolar disorder (manic-depressive illness). This medicine has NOT been approved to treat behavioral problems in older adult patients who have dementia .
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Also known as quetiapine, quetiapine fumarate, 2-(2-(4-dibenzo(b,f)(1,4)thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol, ICI-204636, ICI 204636, Ethanol, 2-(2-(4-dibenzo(b,f)(1,4)thiazepin-11-yl-1-piperazinyl)ethoxy)-, (E)-2-butenedioate (2:1) (salt), Zeneca Brand of Quetiapine Fumarate
Seroquel information from trusted sources:
Seroquel Information from Drugs.com
May 13, 2010 ... Seroquel (quetiapine) treats the symptoms of schizophrenia and bipolar disorder. Includes Seroquel side effects, interactions and ... Read more on
www.drugs.com
seroquel xr medication guide
Read this Medication Guide before you start taking SEROQUEL. XR and each time you get a refill ... SEROQUEL XR can raise the risk of death in elderly people ... Read more on
www.fda.gov
Seroquel - Dosage - Drugs - EverydayHealth.com
Seroquel 100 mg, yellow, round, film coated; Seroquel 200 mg, white, round, film coated; Seroquel, dosage; Take exactly as prescribed by your doctor. Read more on
www.everydayhealth.com
Seroquel
SEROQUEL (quetiapine fumarate) is a psychotropic agent belonging to a chemical class, the dibenzothiazepine derivatives. The chemical designation is 2-[2-(4-dibenzo [b,f] [1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol fumarate (2:1) (salt). It is present in tablets as the fumarate salt. All doses and tablet strengths are expressed as milligrams of base, not as fumarate salt. Its molecular formula is C42H50N6O4S2&bull,C4H4O4 and it has a molecular weight of 883.11 (fumarate salt). The structural formula is:Quetiapine fumarate is a white to off-white crystalline powder which is moderately soluble in water. SEROQUEL is an atypical antipsychotic agent indicated for Bipolar Disorder including: Bipolar Depression (1.1), Bipolar Mania (1.1), Bipolar Maintenance (1.1), and Schizophrenia (1.2) 1.1 Bipolar Disorder 1.2 Schizophrenia 2 DOSAGE AND ADMINISTRATION 2.1 Bipolar Disorder 2.2 Schizophrenia 2.3 Dosing in Special Populations 2.4 Maintenance Treatment 2.5 Reinitiation of Treatment in Patients Previously Discontinued 2.6 Switching from Antipsychotics 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS 5.1 Increased Mortality in Elderly Patients with Dementia-Related Psychosis 5.2 Clinical Worsening and Suicide Risk 5.3 Hyperglycemia and Diabetes Mellitus 5.4 Hyperlipidemia 5.5 Weight Gain 5.6 Neuroleptic Malignant Syndrome (NMS) 5.7 Tardive Dyskinesia 5.8 Orthostatic Hypotension 5.9 Leukopenia, Neutropenia and Agranulocytosis 5.10 Cataracts 5.11 Seizures 5.12 Hypothyroidism 5.13 Hyperprolactinemia 5.14 Increases in Blood Pressure (Children and Adolescents) 5.15 Transaminase Elevations 5.16 Potential for Cognitive and Motor Impairment 5.17 Priapism 5.18 Body Temperature Regulation 5.19 Dysphagia 5.20 Suicide 5.21 Use in Patients with Concomitant Illness 5.22 Withdrawal 6 ADVERSE REACTIONS 6.1 Clinical Study Experience 6.2 Vital Signs and Laboratory Values 6.3 Post Marketing Experience 7 DRUG INTERACTIONS 7.1 The Effect of Other Drugs on Quetiapine... Read more on
dailymed.nlm.nih.gov
Zyprexa Laswuit; Risperdal Lawsuit; Seroquel Lawsuit; Explanation ...
Jan 4, 2010 ... Zyprexa, like Risperdal and Seroquel, has been associated with serious .... News of Seroquel's side effects and emerged as a result of ... Read more on
www.coreynahman.com
Pharmaceutical Giant AstraZeneca to Pay $520 Million for Off-label ...
based company signed a civil settlement to resolve allegations that by marketing Seroquel for unapproved uses, the company caused false claims for payment ... Read more on
www.justice.gov
Contents
Description and Clinical Pharmacology
SEROQUEL® (quetiapine fumarate) is a psychotropic agent belonging to a chemical class, the dibenzothiazepine derivatives. The chemical designation is 2-[2-(4-dibenzo [ b,f ] [1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol fumarate (2:1) (salt). It is present in tablets as the fumarate salt. All doses and tablet strengths are expressed as milligrams of base, not as fumarate salt. Its molecular formula is C42H50N6O4S2•C4H4O4 and it has a molecular weight of 883.11 (fumarate salt)....
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www.druglib.com
Drug Interactions, Overdosage and Contraindications
Phenytoin: Coadministration of quetiapine (250 mg tid) and phenytoin (100 mg tid) increased the mean oral clearance of quetiapine by 5-fold. Increased doses of SEROQUEL may be required to maintain control of symptoms of schizophrenia in patients receiving quetiapine and phenytoin, or other hepatic enzyme inducers (e.g., carbamazepine, barbiturates, rifampin, glucocorticoids). Caution should be taken if phenytoin is withdrawn and replaced with a non-inducer (e.g., valproate) (see DOSAGE AND ADMINISTRATION).
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Indications and Dosage
depressive episodes associated with bipolar disorder acute manic episodes associated with bipolar I disorder as either monotherapy or adjunct therapy to lithium or divalproex.
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Other Rx Information
Physical and Psychologic dependence: SEROQUEL has not been systematically studied, in animals or humans, for its potential for abuse, tolerance or physical dependence. While the clinical trials did not reveal any tendency for any drug-seeking behavior, these observations were not systematic and it is not possible to predict on the basis of this limited experience the extent to which a CNS-active drug will be misused, diverted, and/or abused once marketed. Consequently, patients should be evaluated...
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www.druglib.com
Precautions
Your doctor should check your progress at regular visits, especially during the first few months of treatment with this medicine. This will allow your dosage to be changed if necessary to meet your needs .
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www.mayoclinic.com
Proper Use
Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more or less of it and do not take it more or less often than your doctor ordered .
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www.mayoclinic.com
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
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www.mayoclinic.com
Summary
SEROQUEL (quetiapine fumarate) is a psychotropic agent belonging to a new chemical class, the dibenzothiazepine derivatives. The chemical designation is 2-[2-(4-dibenzo [ b,f ] [1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol fumarate (2:1) (salt). It is present in tablets as the fumarate salt. All doses and tablet strengths are expressed as milligrams of base, not as fumarate salt.
Read more on
www.druglib.com