simvastatin (zocor) information from trusted sources:
Simvastatin is used together with a proper diet to treat high cholesterol levels in the blood. Using this medicine may help prevent medical problems caused by such substances clogging the blood vessels. This medicine may also be used to prevent certain types of heart problems in patients with risk factors for heart problems .
SIMCOR tablets contain niacin extended-release (NIASPAN) and simvastatin in combination. Simvastatin, an inhibitor of HMG-CoA reductase, and niacin are both lipid-altering agents. SIMCOR is a combination of simvastatin, an HMG-Co-A reductase inhibitor, and extended-release niacin (Niaspan), nicotinic acid. SIMCOR is indicated to: 1.1 Patients with Hypercholesterolemia Requiring Modifications of Lipid Profiles 2 DOSAGE AND ADMINISTRATION 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS 5.1 Myopathy/Rhabdomyolysis 5.2 Liver Dysfunction 5.3 Laboratory Abnormalities 6 ADVERSE REACTIONS 6.1 Clinical Studies Experience 7 DRUG INTERACTIONS 7.1 CYP3A4 Inhibitors 7.2 Cyclosporine or Danazol 7.3 Amiodarone or Verapamil 7.4 Gemfibrozil and other Fibrates 7.5 Propranolol 7.6 Digoxin 7.7 Coumarin Anticoagulants 7.8 Aspirin 7.9 Antihypertensive Therapy 7.10 Bile Acid Sequestrants 7.11 Other 8 USE IN SPECIFIC POPULATIONS 8.1 Pregnancy 8.3 Nursing Mothers 8.4 Pediatric Use 8.5 Geriatric Use 8.6 Gender 8.7 Renal Impairment 8.8 Hepatic Impairment 10 OVERDOSAGE 11 DESCRIPTION 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of Action 12.2 Pharmacodynamics 12.3 Pharmacokinetics 13 NONCLINICAL TOXICOLOGY 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility 13.2 Animal Toxicology and/or Pharmacology 14 CLINICAL STUDIES 14.1 Modifications of Lipid Profiles 16 HOW SUPPLIED/STORAGE AND HANDLING 17 PATIENT COUNSELING INFORMATION 17.1 Dosing Time 17.2 Tablet Integrity 17.3 Dosing Interruption 17.4 Muscle Pain 17.5 Flushing 17.6 Use of Aspirin or other Non-Inflammatory Medication 17.7 Diet 17.8 Supplements 17.9 Dizziness 17.10 Diabetics 17.11 Pregnancy 17.12 Breastfeeding FULL PRESCRIBING INFORMATION...