What is TB skin test?

Trichophyton extract for diagnostic skin testing is a sterile solution that is prepared by extracting allergenic source material of equal parts of Trichophyton mentagrophytes and Trichophyton rubrum with an aqueous solution of 0.25% sodium chloride, 0.125% sodium bicarbonate and 50% glycerol v/v. Phenol is added at 0.4% w/v as a preservative. Extract for intradermal administration is diluted with the above solution without glycerol. WEIGHT BY VOLUME (W/V) Weight by volume refers to the weight of raw product added to a measured volume of extraction solution. A 1:500 w/v extract contains 1 gram of source material in 500 mL of solution. The w/v designation refers to concentration rather than potency. Extract labeled w/v has no U.S. Standard of Potency. Intradermal skin tests with Trichophyton extract are indicated for use in persons who are suspected of having Type I hypersensitivity (i.e. allergy) to the fungus.

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Also known as ppd, mantoux, tuberculin skin test, ppd skin test, purified protein derivative, purified protein derivative standard, latent tuberculosis infection test
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An infectious disease caused by the tubercle bacillus, Mycobacterium tuberculosis, and characterized pathologically by inflammatory infiltrations, formation of tubercles, caseation, necrosis, abscesses, fibrosis, and calcification. It most commonly affects the respiratory system but other parts of the body such as gastrointestinal and genitourinary tracts, bones, joints, nervous system, lymph nodes, and skin may become infected. Fish, amphibians, birds, and mammals (esp. cattle) are subject to the disease. Three types of tubercle bacillus exist, namely, human, bovine, and avian. Man may become infected by any of the three types but in the U.S.A., the human type predominates. Infection usually is acquired from contact with an infected person or an infected cow or trough drinking contaminated milk. Tuberculosis may occur in an acute generalized form (miliary tuberculosis) or in a chronic localized form. In man, the primary infection usually consists of a localized lesion and regional adenitis, these constituting the primary complex. From this state, lesions may heal by fibrosis and calcification and the disease exist in an arrested or inactive stage. Reactivation or exacerbation of the disease or reinfection gives rise to the chronic progressive form. Many varieties of Mycobacteria that previously were thought to be nonpathogenic for man have been found to cause chronic progressive pulmonary disease closely resembling pulmonary tuberculosis. These organisms have been termed anonymous or atypical Mycobacteria. They have been classified into four groups: photochromogens, scotochromogens, nonphotochromagens, and rapid growers.

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Tuberculosis Skin Test (PPD Skin Test) Information on MedicineNet.com

Mar 9, 2011 ... The tuberculosis skin test (also known as the tuberculin or PPD test) determines whether a person has developed an immune response to the ...

Read more on www.medicinenet.com

CDC | TB | Fact Sheets - Tuberculin Skin Testing for TB

The Mantoux tuberculin skin test (TST) is the standard method of determining ... For persons scheduled to receive a TST, testing should be done as follows: ...

Read more on www.cdc.gov

Tuberculin Skin Tests

Apr 23, 2009 ... A tuberculin skin test is done to see if you have ever had tuberculosis (TB) (Mycobacterium tuberculosis). It is done by putting a small ...

Read more on www.webmd.com

Mantoux test - Wikipedia, the free encyclopedia

It is one of the two major tuberculin skin tests used in the world, largely replacing ... If a person has had a history of a positive tuberculin skin test, ...

Read more on en.wikipedia.org


Tuberculosis (TB) is a contagious bacterial infection that most frequently affects the lungs. In addition, TB involves other areas of the body, such as the lymph nodes, genitourinary tract, bones, joints, the membranes covering the brain (meninges), and the membranes covering the digestive organs (peritoneum).

Read more on www.pdrhealth.com


If you are diagnosed with pulmonary tuberculosis (TB) you will be contagious until you have been receiving treatment for between two to three weeks.

Read more on www.nhs.uk


Purified Protein Derivative
To help determine whether or not you may have been exposed to and become infected with the Mycobacterium tuberculosis bacteria

Read more on www.labtestsonline.org
PPD skin test
The PPD skin test is a method used to diagnose tuberculosis. PPD stands for purified protein derivative.

Read more on www.nlm.nih.gov
Histoplasma skin test
Histoplasma skin test is a method to check if you have been exposed to a fungus called Histoplasma capsulatum. The fungus causes an infection called histoplasmosis.

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Allergy testing
Allergy tests are any of several tests used to determine the substances to which a person is allergic.

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CSD skin test
The CSD skin test was once used to help diagnose cat scratch disease. The test is rarely used today and is not recommended. There are better methods, such as antibody detection by the EIA test, available to diagnose cat scratch disease.

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Allergy skin tests
During an allergy skin test, your skin is exposed to allergy-causing substances (allergens) and then is observed for signs of a local allergic reaction.

Read more on www.mayoclinic.com
Lepromin skin test
The lepromin skin test is used to determine what type of leprosy a person has.

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Coccidioidin skin test
The coccidiodin skin test checks to see if you are infected with the fungus that causes coccidioidomycosis. The spherulin test also looks for this fungus, but it may be a more sensitive test. That means it may pick up signs of the infection earlier or more accurately.

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Histamine Dihydrochloride contains histamine, a potent vasodilator having the chemical name 2-(4-Imidazolyl) ethylamine. Histamine has an empirical formula of C5H9N3, a molecular weight of 111.15, and the following chemical structure:Histamine Dihydrochloride is available in the following strengths: 1. SCRATCH, PRICK or PUNCTURE TEST CONTROL: Positive Skin Test Control - Histamine contains 6.0 mg/mL Histamine Base and is a clear, colorless, sterile solution. It consists of Histamine Dihydrochloride 10mg/mL, Sodium Chloride 0.5%, Sodium Bicarbonate 0.275%, and Glycerin 50.0% (v/v) as a preservative. Positive Skin Test Control - Histamine is indicated as an adjunct in allergy skin test for diagnosis, as a positive control to test wheal-flare response of skin for evaluation of skin test response to allergenic extracts.

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Tuberculin tine test
The test results may be incorrect (false negative). False negative means the test suggests you haven't been exposed to tuberculosis, but you really have been. Incorrect results are more common with this test than with the tuberculin skin test.

Read more on www.nlm.nih.gov
Tuberculosis (TB) is a potentially serious infectious disease that primarily affects your lungs. Tuberculosis is spread from person to person through tiny droplets released into the air. Most people who become infected with the bacteria that cause tuberculosis don't develop symptoms of the disease.

Read more on www.mayoclinic.com