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What is voriconazole?
Voriconazole is used to treat different kinds of serious fungal infections. It may also be used to treat patients with serious fungal infections who cannot tolerate other types of treatment or do not respond to other types of treatment.
Read more on www.mayoclinic.com
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voriconazole information from trusted sources:
Vfend
VFEND I.V.(voriconazole) for InjectionVFEND Tablets (voriconazole)VFEND (voriconazole) for Oral Suspension Read more on
www.druglib.com
Voriconazole
Voriconazole is used to treat serious fungal infections such as invasive aspergillosis (a fungal infection that begins in the lungs and spreads through the bloodstream to other organs) and esophageal candidiasis (infection by a yeast-like fungus that may cause white patching in the mouth and throat). Voriconazole is in a class of antifungal medications called triazoles. It works by slowing the growth of the fungi that cause infection. Read more on
www.nlm.nih.gov
Vfend I.V.
Voriconazole is used to treat different kinds of serious fungal infections. It may also be used to treat patients with serious fungal infections who cannot tolerate other types of treatment or do not respond to other types of treatment. Read more on
www.mayoclinic.com
Voriconazole - Wikipedia, the free encyclopedia
Voriconazole (VFEND, Pfizer) is a triazole antifungal medication that is generally used to treat serious, invasive fungal infections. ... Read more on
en.wikipedia.org
Vfend (Voriconazole) Drug Information: User Reviews, Side Effects ...
Learn about the prescription medication Vfend (Voriconazole), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Read more on
www.rxlist.com
voriconazole consumer information from Drugs.com
voriconazole patient information. Detailed drug information for the consumer, includes dosage, voriconazole side effects and more. Read more on
www.drugs.com
VORICONAZOLE - ORAL (Vfend) side effects, medical uses, and drug ...
Mar 15, 2011 ... Consumer information about the medication VORICONAZOLE - ORAL (Vfend), includes side effects, drug interactions, recommended dosages, ... Read more on
www.medicinenet.com
Monitoring of Voriconazole and Posaconazole: Abstract and Introduction
Feb 17, 2011 ... Abstract and Introduction: Can dosing of these antifungals be individualized? Read more on
www.medscape.com
Voriconazole
Nov 2, 2010 ... Although not robustly prospectively studied, voriconazole trough concentrations <1 mg/L with higher rates of failure in treatment of ... Read more on
hopkins-abxguide.org
Voriconazole: the newest triazole antifungal agent
by ND Greer - 2003 - Cited by 22 - Related articles Read more on
scholar.google.com
Contents
Description and Clinical Pharmacology
VFEND® (voriconazole), a triazole antifungal agent, is available as a lyophilized powder for solution for intravenous infusion, film-coated tablets for oral administration, and as a powder for oral suspension. The structural formula is: Voriconazole is designated chemically as (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1 H -1,2,4-triazol-1-yl)-2-butanol with an empirical formula of C16H14F3N5O and a molecular weight of 349.3.
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www.druglib.com
Drug Interactions, Overdosage and Contraindications
Tables 11 and 12 provide a summary of significant drug interactions with voriconazole that either have been studied in vivo (clinically) or that may be expected to occur based on results of in vitro metabolism studies with human liver microsomes. For more details, see CLINICAL PHARMACOLOGY - Drug Interactions.
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www.druglib.com
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
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www.nlm.nih.gov
Indications and Dosage
Invasive aspergillosis. In clinical trials, the majority of isolates recovered were Aspergillus fumigatus. There was a small number of cases of culture-proven disease due to species of Aspergillus other than A. fumigatus (see CLINICAL STUDIES, MICROBIOLOGY).
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www.druglib.com
Medicine storage
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not refrigerate or freeze the medication. Throw away any medication that is outdated or no longer needed. Throw away any unused suspension after 14 days. Talk to your pharmacist about the proper disposal of your medication.
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www.nlm.nih.gov
Missed dose
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
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www.nlm.nih.gov
Other Rx Information
Clinical Laboratory Standards Institute. Reference method for broth dilution antifungal susceptibility testing of conidium-forming filamentous fungi. Approved Standard M38-P. Clinical Laboratory Standards Institute, Villanova, Pa. Clinical Laboratory Standards Institute. Reference method for broth dilution antifungal susceptibility testing of yeasts. Approved Standard M27-A. Clinical Laboratory Standards Institute, Villanova, Pa. Clinical Laboratory Standards Institute. Method for antifungal...
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www.druglib.com
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
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www.nlm.nih.gov
Precautions
It is very important that your doctor check you at regular visits to see if the medicine is working properly and decide if you should continue to take it.
Read more on
www.mayoclinic.com
Proper use
Voriconazole comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken every 12 hours on an empty stomach, at least 1 hour before or 1 hour after a meal. To help you remember to take voriconazole, take it at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take voriconazole exactly as directed. Do not take more or less of it or take it more often than...
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www.nlm.nih.gov
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
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www.mayoclinic.com
Side Effects and Adverse Reactions
The most frequently reported adverse events (all causalities) in the therapeutic trials were visual disturbances, fever, rash, vomiting, nausea, diarrhea, headache, sepsis, peripheral edema, abdominal pain, and respiratory disorder. The treatment-related adverse events which most often led to discontinuation of voriconazole therapy were elevated liver function tests, rash, and visual disturbances (see hepatic toxicity under WARNINGS and discussion of Clinical Laboratory Values and dermatological...
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www.druglib.com
Special diatery instructions
Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine.
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www.nlm.nih.gov
Special precautions
Before taking voriconazole,tell your doctor and pharmacist if you are allergic to voriconazole; other antifungal medications such as fluconazole (Diflucan), itraconazole (Sporonox), or ketoconazole (Nizoral); or any other medications..
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www.nlm.nih.gov
Summary
VFEND® I.V.(voriconazole) for InjectionVFEND® Tablets (voriconazole)VFEND® (voriconazole) for Oral Suspension
Read more on
www.druglib.com
Uses
Voriconazole is used to treat serious fungal infections such as invasive aspergillosis (a fungal infection that begins in the lungs and spreads through the bloodstream to other organs) and esophageal candidiasis (infection by a yeast-like fungus that may cause white patching in the mouth and throat). Voriconazole is in a class of antifungal medications called triazoles. It works by slowing the growth of the fungi that cause infection.
Read more on
www.nlm.nih.gov