What is Zolpidem?

Zolpidem information from trusted sources:

Zolpidem

Zolpidem is used to treat insomnia (difficulty falling asleep or staying asleep). Zolpidem belongs to a class of medications called sedative-hypnotics. It works by slowing activity in the brain to allow sleep.

Ambien

Zolpidem belongs to the group of medicines called central nervous system (CNS) depressants (medicines that slow down the nervous system). Zolpidem is used to treat insomnia (trouble in sleeping). Zolpidem helps you get to sleep faster and sleep through the night. In general, when sleep medicines are used every night for a long time, they may lose their effectiveness. In most cases, sleep medicines should be used only for short periods of time, such as 1 or 2 days, and generally for no longer than 1 or 2 weeks.

Ambien CR

Ambien CR contains zolpidem tartrate, a non-benzodiazepine hypnotic of the imidazopyridine class. Ambien CR (zolpidem tartrate extended-release tablets) is available in 6.25 mg and 12.5 mg strength tablets for oral administration. Ambien CR is indicated for the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance. (1) 2 DOSAGE AND ADMINISTRATION 2.1 Dosage in adults 2.2 Special populations 2.3 Use with CNS depressants 2.4 Administration 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS 5.1 Need to evaluate for co-morbid diagnoses 5.2 Severe anaphylactic and anaphylactoid reactions 5.3 Abnormal thinking and behavioral changes 5.4 Withdrawal effects 5.5 CNS depressant effects 5.6 Special populations 6 ADVERSE REACTIONS 6.1 Clinical trials experience 7 DRUG INTERACTIONS 7.1 CNS-active drugs 7.2 Drugs that affect drug metabolism via cytochrome P450 7.3 Other drugs with no interaction with zolpidem 7.4 Drug-laboratory test interactions 8 USE IN SPECIFIC POPULATIONS 8.1 Pregnancy 8.2 Labor and delivery 8.3 Nursing mothers 8.4 Pediatric use 8.5 Geriatric use 9 DRUG ABUSE AND DEPENDENCE 9.1 Controlled substance 9.2 Abuse 9.3 Dependence 10 OVERDOSAGE 10.1 Signs and symptoms 10.2 Recommended treatment 11 DESCRIPTION 12 CLINICAL PHARMACOLOGY 12.1 Mechanism of action 12.3 Pharmacokinetics 13 NONCLINICAL TOXICOLOGY 13.1 Carcinogenesis, mutagenesis, impairment of fertility 14 CLINICAL STUDIES 14.1 Controlled clinical trials 14.2 Studies pertinent to safety concerns for sedative/hypnotic drugs 16 HOW SUPPLIED/STORAGE AND HANDLING 17 PATIENT COUNSELING INFORMATION 17.1 Severe anaphylactic and anaphylactoid reactions 17.2 Sleep-driving and other complex behaviors 17.3 Administration instructions 17.4 Medication Guide FULL PRESCRIBING INFORMATION...

Ambien CR

Ambien CR contains zolpidem tartrate, a non-benzodiazepine hypnotic of the imidazopyridine class.

Ambien CR

Ambien CR belongs to a group of medicines known as sedative/hypnotics, or sleep medicines. Ambien CR is used for the short-term treatment of insomnia, which includes trouble falling asleep, waking up too early in the morning, or waking up often during the night.

Ambien CR

An immediate-release formulation of zolpidem tartrate was evaluated in healthy subjects in single-dose interaction studies for several CNS drugs. A study involving haloperidol and zolpidem tartrate revealed no effect of haloperidol on the pharmacokinetics or pharmacodynamics of zolpidem. Imipramine in combination with zolpidem tartrate produced no pharmacokinetic interaction other than a 20% decrease in peak levels of imipramine, but there was an additive effect of decreased alertness. Similarly,...

Ambien CR

In clinical trials with Ambien CR, 3.5% of 201 patients receiving 6.25-mg or 12.5-mg of Ambien CR discontinued treatment because of an adverse event. Events most commonly associated with discontinuation were somnolence (1.0%) and dizziness (1.0%).

Ambien CR

Because sleep disturbances may be the presenting manifestation of a physical and/or psychiatric disorder, symptomatic treatment of insomnia should be initiated only after a careful evaluation of the patient. The failure of insomnia to remit after 7 to 10 days of treatment may indicate the presence of a primary psychiatric and/or medical illness that should be evaluated. Worsening of insomnia or the emergence of new thinking or behavior abnormalities may be the consequence of an unrecognized...

Ambien CR

Ambien CR (zolpidem tartrate extended-release tablets) is indicated for the treatment of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance (as measured by wake time after sleep onset). (See Clinical Pharmacology: Controlled trials supporting safety and efficacy.)